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Table 1 Characteristics of all included patients are reported

From: Prophylactic bilateral central neck dissection should be evaluated based on prospective randomized study of 581 PTC patients

Characteristics

ICND

(Control group)

BCND

(Test group)

p value

No. of patients

296

285

/

Age [years; ±SD (range)]

43.2 ± 11.7

43.8 ± 11.5

0.544

Male/female

70/226

72/213

0.939

Pathological tumor size [mm; ±SD (range)]

8.3 ± 5.0

8.8 ± 5.5

0.356

Operative time [min; ±SD (range)]

50.5 ± 10.4

60.4 ± 11.5

0.006

Pathological T classification (<T3/T3)

157/139

167/118

0.178

Pathological N classification(p N0 / p N1a)

134/162

96/189

0.004

Tumor side/contralateral side (+/+)

/

61

/

Tumor side/contralateral side (+/−)

/

124

/

Tumor side/contralateral side (−/+)

/

4

/

Tumor side/contralateral side (−/−)

/

96

/

Unifocal/Multifocal

242/54

245/40

0.169

Transient hypocalcemia

40/296

47/285

0.315

Transient laryngeal nerve palsy

13/296

25/285

0.033

Definitive laryngeal nerve palsy

2/296

2/285

1.000

Post-operation hemorrhage

6/296

5/285

1.000

Removed lymph nodes [±SD (range)]

8.5 ± 5.8

12.5 ± 6.5

0.002

Metastasized lymph nodes [±SD (range)]

2.6 ± 1.5

2.88 ± 1.7

0.857

PG numbers of auto-transplantation

226/592

377/855

0.025

The ratio of IONM

90/296

85/285

0.879

PTH (pre-operation)

4.28 ± 1.50

4.18 ± .1.62

0.945

CA (pre-operation)

2.34 + 0.16

2.32 ± 0.10

0.243

PTH (Postoperative 1 Day)

2.83 ± 1.37

2.55 ± 1.21

0.010

CA (Postoperative 1 Day)

2.26 ± 0.10

2.26 ± 0.09

0.556

PTH (Postoperative 6 months)

3.93 ± 1.93

3.95 ± 1.99

0.915

CA (Postoperative 6 months)

2.37 ± 0.93

2.36 ± 0.95

0.949

Number of tumor recurrence

0/296

1/285

0.491