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Fig. 6 | BMC Endocrine Disorders

Fig. 6

From: The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas

Fig. 6

MAPK11 siRNA was transfected into GH3 cells to detect the effect of MAPK11 protein on the expression of PRL, NF-KB p65, Bcl2 and Bax in GH3 cells regulated by bromocriptine. a Western blotting was used to analyse the knockdown efficiency of three MAPK11 siRNA (50 nM, 100 nM) transfected into GH3 cells for 72 h. b The level of PRL in the supernatant of GH3 cells was detected by ELISA.*p < 0.05, ****p < 0.0001 (n = 6). c, d The protein expression levels of PRL, NF-κB p65, Bcl2 and Bax in GH3 cells were analysed by western blotting.*p < 0.05, **p < 0.01, ****p < 0.0001 (n = 3)

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