From: Screening for mild cognitive impairment in people with obesity: a systematic review
Authors, Year, country | Aim of the study | Study Design | Participants’ Age (in years) | Sample Size | Obesity Assessment | Cognitive Screening Tool | Major Findings |
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Yuan et al., [36] China | To investigate gender and age as moderators in the association between BMI and mild cognitive impairment (MCI) among rural older adults | Cross-sectional | Aged 60 and above (Range from 60 to 100 ) Age scategorised into Below 75 and above 75 . | n = 3242 | BMI [sCategorised into underweight (low BMI), normal weight (normal BMI), overweight (elevated BMI) and obese (high BMI)] | MMSE (30 Items; Chinese Version) | Below 75 years (Both men and women) There was no significant difference in MCI among overweight and obese categories when compared to normal BMI. (p>0.05) Above 75 years. Older men Compared to nomal BMI category, Overweight category had higher risk of MCI (aOR = 2.32, 95 % CI: 1.17–4.61; p<0.05) Older women BMI (overweight and Obesity) vs. MCI – NS |
Salama et al., [37] Egypt | To assess MCI prevalence and its relation with lifestyle risk factors among obese adults | Case-control | Mean age case (Obese) – 52.1± 5 Mean age control (Healthy) – 51.3± 6 | Case (Obesity) n=161 Control (Healthy) n=69 | BMI Obesity Gr. I (BMI <35) Obesity Gr. II (BMI 35-39.9) Obesity Gr. III (BMI>40) | ACE (Version III) | MCI was assessed between Obesity categories (I, II and III) and control (healthy adults) MCI between Grade I and Control (OR – 5.5, 95 % CI: 2.2-13.5; p<0.001) MCI between Grade II and Control (OR – 6.8, 95 % CI: 2.7-16.9; p<0.001) MCI between Grade III and Control (OR – 4.8, 95 % CI: 1.8-12.5; p<0.001) |