Variables | Hypothyroidism N = 614 | Normal Control N = 7329 | P value | Total N = 7943 |
---|---|---|---|---|
Vitamin D categories, % (SE) | < 0.001 | |||
Deficient (< 20 ng/mL) | 25.6% (1.9) | 20.6% (1.3) | 21.0% (1.2) | |
Intermediate (20 to < 30 g/mL) | 38.1% (1.9) | 32.7% (0.8) | 33.1% (0.7) | |
Optimal (≥30 ng/mL) | 36.3% (1.7) | 46.7% (1.2) | 45.9% (1.1) | |
BMI (kg/m2), % (SE) | < 0.001 | |||
Underweight (< 18.5 kg/m2) | 1.3% (0.6) | 1.8% (0.2) | 1.7% (0.2) | |
Normal (18.5–24.9 kg/m2) | 25.3% (1.6) | 30.2% (0.8) | 29.8% (0.7) | |
Overweight (25.0–29.9 kg/m2) | 33.0% (2.8) | 34.2% (0.8) | 34.1% (0.8) | |
Obese (≥30.0 kg/m2) | 40.5% (3.0) | 33.8% (0.8) | 34.4% (0.8) | |
Hypertension, % (SE) | 47.1% (2.9) | 29.5% (0.7) | < 0.001 | 30.9% (0.7) |
Diabetes, % (SE) | 19.7% (2.4) | 10.7% (0.5) | < 0.001 | 11.5% (0.5) |
Dyslipidemia, % (SE) | 54.9% (2.3) | 44.7% (0.8) | < 0.001 | 45.5% (0.7) |
Thyroglobulin antibodies (IU/mL) | 68.1 (3.2) | 6.4 (0.8) | < 0.001 | 11.3 (1.3) |
Thyroid peroxidase antibodies (IU/mL) | 87.2 (8.6) | 15.8 (1.2) | < 0.001 | 21.3 (1.2) |
Total protein (g/L) | 70.7 (0.3) | 71.3 (0.1) | 0.145 | 71.2 (0.1) |
Albumin (g/L) | 41.9 (0.2) | 42.9 (0.1) | < 0.001 | 42.8 (0.1) |
Alanine aminotransferase (U/L) | 25.2 (1.1) | 25.9 (0.2) | 0.522 | 25.8 (0.2) |
Aspartate aminotransferase (U/L) | 27.6 (1.2) | 25.9 (0.2) | 0.211 | 26 (0.2) |
Alkaline phosphatase (U/L) | 68.6 (1.4) | 66.7 (0.4) | 0.139 | 66.8 (0.4) |
Total bilirubin (mg/dL) | 0.74 (0.1) | 0.8 (0.1) | 0.068 | 0.8 (0.1) |
Iodine, urine (ug/L) | 381.7 (63.2) | 248.8 (12.6) | 0.077 | 259.5 (13.6) |
Direct HDL-Cholesterol (mg/dL) | 55 (1.1) | 52.2 (0.3) | 0.008 | 52.4 (0.3) |
LDL-cholesterol (mg/dL) | 117 (1.0) | 116.4 (0.6) | 0.849 | 116.4 (0.6) |
Total Cholesterol (mg/dL) | 198.3 (1.2) | 196.9 (0.7) | 0.514 | 197 (0.6) |
Triglyceride (mg/dL) | 131.8 (2.2) | 134 (2.9) | 0.710 | 133.8 (2.6) |
Creatinine (mg/dL) | 0.88 (0.1) | 0.9 (0.01) | 0.434 | 0.9 (0) |
Blood urea nitrogen (mg/dL) | 14.4 (0.2) | 12.9 (0.1) | < 0.001 | 13 (0.1) |
Chloride (mmol/L) | 103.3 (0.2) | 104 (0.1) | < 0.001 | 104 (0.1) |
Phosphorus (mg/dL) | 3.8 (0.1) | 3.8 (0.1) | 0.002 | 3.8 (0.1) |
Potassium (mmol/L) | 4.0 (0.1) | 4.0 (0.1) | 0.059 | 4.0 (0.1) |
Sodium (mmol/L) | 139 (0.1) | 139.2 (0.1) | 0.226 | 139.2 (0.1) |
Total calcium (mg/dL) | 9.4 (0.1) | 9.4 (0.2) | 0.018 | 9.4 (0.2) |