Skip to main content

Table 2 Clinical characteristics of the participants, NHANES 2007–2012 (N = 7943)

From: Association between vitamin D deficiency and hypothyroidism: results from the National Health and Nutrition Examination Survey (NHANES) 2007–2012

Variables Hypothyroidism
N = 614
Normal Control
N = 7329
P value Total
N = 7943
Vitamin D categories, % (SE)    < 0.001  
Deficient (< 20 ng/mL) 25.6% (1.9) 20.6% (1.3)   21.0% (1.2)
Intermediate (20 to < 30 g/mL) 38.1% (1.9) 32.7% (0.8)   33.1% (0.7)
Optimal (≥30 ng/mL) 36.3% (1.7) 46.7% (1.2)   45.9% (1.1)
BMI (kg/m2), % (SE)    < 0.001  
Underweight (< 18.5 kg/m2) 1.3% (0.6) 1.8% (0.2)   1.7% (0.2)
Normal (18.5–24.9 kg/m2) 25.3% (1.6) 30.2% (0.8)   29.8% (0.7)
Overweight (25.0–29.9 kg/m2) 33.0% (2.8) 34.2% (0.8)   34.1% (0.8)
Obese (≥30.0 kg/m2) 40.5% (3.0) 33.8% (0.8)   34.4% (0.8)
Hypertension, % (SE) 47.1% (2.9) 29.5% (0.7) < 0.001 30.9% (0.7)
Diabetes, % (SE) 19.7% (2.4) 10.7% (0.5) < 0.001 11.5% (0.5)
Dyslipidemia, % (SE) 54.9% (2.3) 44.7% (0.8) < 0.001 45.5% (0.7)
Thyroglobulin antibodies (IU/mL) 68.1 (3.2) 6.4 (0.8) < 0.001 11.3 (1.3)
Thyroid peroxidase antibodies (IU/mL) 87.2 (8.6) 15.8 (1.2) < 0.001 21.3 (1.2)
Total protein (g/L) 70.7 (0.3) 71.3 (0.1) 0.145 71.2 (0.1)
Albumin (g/L) 41.9 (0.2) 42.9 (0.1) < 0.001 42.8 (0.1)
Alanine aminotransferase (U/L) 25.2 (1.1) 25.9 (0.2) 0.522 25.8 (0.2)
Aspartate aminotransferase (U/L) 27.6 (1.2) 25.9 (0.2) 0.211 26 (0.2)
Alkaline phosphatase (U/L) 68.6 (1.4) 66.7 (0.4) 0.139 66.8 (0.4)
Total bilirubin (mg/dL) 0.74 (0.1) 0.8 (0.1) 0.068 0.8 (0.1)
Iodine, urine (ug/L) 381.7 (63.2) 248.8 (12.6) 0.077 259.5 (13.6)
Direct HDL-Cholesterol (mg/dL) 55 (1.1) 52.2 (0.3) 0.008 52.4 (0.3)
LDL-cholesterol (mg/dL) 117 (1.0) 116.4 (0.6) 0.849 116.4 (0.6)
Total Cholesterol (mg/dL) 198.3 (1.2) 196.9 (0.7) 0.514 197 (0.6)
Triglyceride (mg/dL) 131.8 (2.2) 134 (2.9) 0.710 133.8 (2.6)
Creatinine (mg/dL) 0.88 (0.1) 0.9 (0.01) 0.434 0.9 (0)
Blood urea nitrogen (mg/dL) 14.4 (0.2) 12.9 (0.1) < 0.001 13 (0.1)
Chloride (mmol/L) 103.3 (0.2) 104 (0.1) < 0.001 104 (0.1)
Phosphorus (mg/dL) 3.8 (0.1) 3.8 (0.1) 0.002 3.8 (0.1)
Potassium (mmol/L) 4.0 (0.1) 4.0 (0.1) 0.059 4.0 (0.1)
Sodium (mmol/L) 139 (0.1) 139.2 (0.1) 0.226 139.2 (0.1)
Total calcium (mg/dL) 9.4 (0.1) 9.4 (0.2) 0.018 9.4 (0.2)