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Table 6 Hazard ratios of acute cardiac injury according to different FT3 categories among patients with COVID-19

From: Suppression of the hypothalamic-pituitary-thyroid axis is associated with the severity of prognosis in hospitalized patients with COVID-19

  No of participants No. of cases Person-days Hazard ratios (95% confidence intervals)
Model 1 Model 2 Model 3
Acute cardiac injury
 Normal FT3a, 205 33 6396 1.00 1.00 1.00
 Low FT3b 30 17 916 2.39 (1.20–4.77) 2.47 (1.13–5.37) 3.46 (1.90–6.31)
  1. Model 1 adjusted for age and sex. Model 2 adjusted for age, sex, smoking, systolic blood pressure, fasting glucose, using antihypertensive drugs, and using glucose-lowering drug. Model 3 adjusted for total cholesterol and using lipid-lowering agents. aNormal FT3 was defined as FT3 within 2.63–5.7 pmol/L. bLow FT3 was defined as FT3 < 2.63 pmol/L. Abbreviations: COVID-19 coronavirus disease 2019, FT3 Free Triiodothyronine