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Table 1 General Characteristics of subjects

From: Quantitative evaluation of activity of thyroid-associated Ophthalmopathy using short-tau inversion recovery (STIR) sequence

  Control
(n = 31)
TAO P-Value
Inactive
(n = 26)
Active
(n = 25)
Inactive vs. Control Active vs. Control Active vs. Inactive
Eyes 62 51 51
Age (year) 46.10 ± 15.45 43.00 ± 12.93 51.56 ± 10.23 0.42 0.13 0.02
Male, n (%) 12 (38.71) 10 (38.46) 14 (56.00) 0.99 0.20 0.21
Duration (m) 6 (3–12) 5 (3–8) 0.24
Smoker, n (%) 4 (12.90) 7 (26.92) 14 (56.00) 0.18 < 0.01 0.02
BMI (kg/m2) 23.03 ± 2.92 22.96 ± 3.16 23.50 ± 2.62 0.93 0.53 0.51
FT3 (pg/ml) 2.94 ± 0.37 5.14 ± 4.48 3.53 ± 0.88 < 0.01 < 0.01 0.08
FT4 (ng/dl) 0.87 ± 0.10 2.17 ± 3.23 1.68 ± 2.64 0.03 0.09 0.56
TSH (μIU/ml) 1.64 (1.18–2.28) 0.15 (0.01–3.03) 0.50 (0.04–3.66) 0.44 0.20 0.75
TPO-Ab 0.60 (0.30–1.15) 44.00 (3.65–125.50) 11.00 (4.60–46.3) < 0.01 0.01 0.98
Tg-Ab 0.10 (0.10–0.10) 0.80 (0.10–9.43) 0.20 (0.10–5.80) < 0.01 0.03 0.57
TR-Ab 0.50 (0.35–0.50) 3.40 (0.90–20.35) 7.30 (3.48–18.70) < 0.01 < 0.01 0.79
Eyesight 0.79 ± 0.25 0.82 ± 0.28 0.66 ± 0.28 0.50 < 0.01 < 0.01
Intraocular pressure (mmHg) 15.36 ± 3.02 17.53 ± 3.65 21.41 ± 4.87 < 0.01 < 0.01 < 0.01
Exophthalmos (mm) 15.66 ± 2.25 18.67 ± 3.62 20.31 ± 2.99 < 0.01 < 0.01 < 0.01
Disease severity
 mild, n (%) 18 (69.23) 1 (4.00) < 0.01
 moderate-severe, n (%) 8 (30.77) 17 (68.00) < 0.01
 very severe, n (%) 0 7 (28.00) < 0.01
  1. Table 1 Data are means ± SD or median (interquartile ranges) or number (percentage) for indicated number of patients in each group. P values for comparisons between groups are based on unpaired t test or Mann-Whitney Test or χ2 test.
  2. Abbreviations: BMI Body mass index, FT3 Free triiodothyronine, FT4 Free thyroxine, Tg-Ab Thyroglobulin antibody, TPO-Ab Thyroid peroxidase antibody, TR-Ab Thyroid stimulating receptor antibody, TSH Thyroid stimulating hormone.