Table 1 General Characteristics of subjects
Control (n = 31) | TAO | P-Value | ||||
|---|---|---|---|---|---|---|
Inactive (n = 26) | Active (n = 25) | Inactive vs. Control | Active vs. Control | Active vs. Inactive | ||
Eyes | 62 | 51 | 51 | – | – | – |
Age (year) | 46.10 ± 15.45 | 43.00 ± 12.93 | 51.56 ± 10.23 | 0.42 | 0.13 | 0.02 |
Male, n (%) | 12 (38.71) | 10 (38.46) | 14 (56.00) | 0.99 | 0.20 | 0.21 |
Duration (m) | – | 6 (3–12) | 5 (3–8) | – | – | 0.24 |
Smoker, n (%) | 4 (12.90) | 7 (26.92) | 14 (56.00) | 0.18 | < 0.01 | 0.02 |
BMI (kg/m2) | 23.03 ± 2.92 | 22.96 ± 3.16 | 23.50 ± 2.62 | 0.93 | 0.53 | 0.51 |
FT3 (pg/ml) | 2.94 ± 0.37 | 5.14 ± 4.48 | 3.53 ± 0.88 | < 0.01 | < 0.01 | 0.08 |
FT4 (ng/dl) | 0.87 ± 0.10 | 2.17 ± 3.23 | 1.68 ± 2.64 | 0.03 | 0.09 | 0.56 |
TSH (μIU/ml) | 1.64 (1.18–2.28) | 0.15 (0.01–3.03) | 0.50 (0.04–3.66) | 0.44 | 0.20 | 0.75 |
TPO-Ab | 0.60 (0.30–1.15) | 44.00 (3.65–125.50) | 11.00 (4.60–46.3) | < 0.01 | 0.01 | 0.98 |
Tg-Ab | 0.10 (0.10–0.10) | 0.80 (0.10–9.43) | 0.20 (0.10–5.80) | < 0.01 | 0.03 | 0.57 |
TR-Ab | 0.50 (0.35–0.50) | 3.40 (0.90–20.35) | 7.30 (3.48–18.70) | < 0.01 | < 0.01 | 0.79 |
Eyesight | 0.79 ± 0.25 | 0.82 ± 0.28 | 0.66 ± 0.28 | 0.50 | < 0.01 | < 0.01 |
Intraocular pressure (mmHg) | 15.36 ± 3.02 | 17.53 ± 3.65 | 21.41 ± 4.87 | < 0.01 | < 0.01 | < 0.01 |
Exophthalmos (mm) | 15.66 ± 2.25 | 18.67 ± 3.62 | 20.31 ± 2.99 | < 0.01 | < 0.01 | < 0.01 |
Disease severity | ||||||
mild, n (%) | – | 18 (69.23) | 1 (4.00) | – | – | < 0.01 |
moderate-severe, n (%) | – | 8 (30.77) | 17 (68.00) | – | – | < 0.01 |
very severe, n (%) | – | 0 | 7 (28.00) | – | – | < 0.01 |