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Table 8 Baseline-reported outcome scores for SF-36 domains in adult patients

From: The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics

SF-36 Domain

rhPTH(1-84)

(n=63)

Conventional therapy

(n=579)

Analysis populationa

(N=642)

n

Value

n

Value

n

Value

Physical functioning

62

43±11.6

525

47±10.1

587

47±10.3

Bodily pain

62

44±10.4

530

47±10.8

592

47±10.8

Role limitation – physical health

62

42±11.4

527

46±11.0

589

46±11.1

Role limitation – emotional problems

62

42±14.4

530

47±11.1

592

47±11.6

General health

61

41±10.4

528

46±11.5

589

45±11.5

Mental health

61

45±12.0

529

49±10.2

590

49±10.5

Social functioning

61

42±11.1

530

47±10.9

591

46±11.0

Vitality

61

42±11.5

529

47±11.1

590

47±11.2

  1. All values are presented as mean ± SD
  2. rhPTH(1-84) recombinant human parathyroid hormone (1-84), SF-36 36-Item Short Form Health Survey questionnaire for adults
  3. aBaseline is defined as the assessment at enrollment (visit 1); pediatric patients (n=27) and those who initiated rhPTH(1-84) before enrollment (n=68) were excluded from the analysis