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Table 7 Doctors’ office visits, emergency department visits, and overnight hospital admissions due to hypoparathyroidism at baselinea

From: The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics

Parameter, n (%) rhPTH(1-84)
(n=60)
Conventional therapy
(n=571)
Analysis populationb
(N=631)
Number of doctors’ office visits  
 0 8 (13.3) 123 (21.5) 131 (20.8)
 1 5 (8.3) 82 (14.4) 87 (13.8)
 2–3 20 (33.3) 148 (25.9) 168 (26.6)
 4–5 6 (10.0) 42 (7.4) 48 (7.6)
 6–7 3 (5.0) 18 (3.2) 21 (3.3)
 8–9 7 (11.7) 15 (2.6) 22 (3.5)
 10–12 3 (5.0) 9 (1.6) 12 (1.9)
 13–15 1 (1.7) 2 (0.4) 3 (0.5)
 ≥16 2 (3.3) 6 (1.1) 8 (1.3)
 Missing 5 (8.3) 126 (22.1) 131 (20.8)
Number of emergency department visits
 0 11 (18.3) 86 (15.1) 97 (15.4)
 1 15 (25.0) 41 (7.2) 56 (8.9)
 2–3 5 (8.3) 25 (4.4) 30 (4.8)
 4–5 3 (5.0) 6 (1.1) 9 (1.4)
 6–7 3 (5.0) 8 (1.4) 11 (1.7)
 8–9 0 (0.0) 0 (0.0) 0 (0.0)
 10–12 1 (1.7) 1 (0.2) 2 (0.3)
 13–15 0 (0.0) 1 (0.2) 1 (0.2)
 ≥16 0 (0.0) 0 (0.0) 0 (0.0)
 Missing 22 (36.7) 403 (70.6) 425 (67.4)
≥1 overnight hospital admission 27 (45.0) 83 (14.5) 110 (17.4)
  1. rhPTH(1-84) recombinant human parathyroid hormone (1-84)
  2. aData are events reported in adult patients that occurred within 12 months before baseline
  3. bBaseline is defined as the assessment at enrollment (visit 1); pediatric patients (n=27), those who received rhPTH(1-34) (n=14), and those who initiated rhPTH(1-84) before enrollment (n=65) were excluded from the analysis