Fig. 4

Pathological results of the resected tumor samples. (A-C) Pathological findings from the third frontal craniotomy. (A) Mitotic activity was increased (HE: 20×). (B) Immunohistochemistry (IHC) of PRL in neoplastic cells was strongly positive (20×). (C) The Ki-67 index was increased to 10% (20×). (D-F) Pathological findings from the fourth frontal craniotomy. (D) Mitotic activity was increased (HE: 20×). (E) IHC of PRL in neoplastic cells was strongly positive (20×). (F) The Ki-67 index was increased to 20% (20×). (G-I) Pathological findings from resected intraspinal tumors. (G) Mitotic activity was increased (HE: 20×); (H) IHC of PRL in neoplastic cells was strongly positive (20×); (I) The Ki-67 index was increased to 30% (20×). H&E: hematoxylin-eosin; PRL: Prolactin