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Table 1 Patient characteristics and initial management

From: A multicenter, prospective study to observe the initial management of patients with differentiated thyroid cancer in China (DTCC study)

Parameter

 

N = 2013

Age (years)

Median (range)

41.8 (13.9-88.2)

  ≥ 55

n (%)

231 (11.5)

 45–55

n (%)

530 (26.3)

  <  45

n (%)

1252 (62.2)

Female sex

n (%)

1445 (71.8)

Family history of thyroid cancer

n (%)

38 (1.9)

 Thyroiditis

n (%)

20 (1.0)

 Hyperthyroidism

n (%)

36 (1.8)

 Hypothyroidism

n (%)

9 (0.4)

 Thyroid nodules

n (%)

666 (33.1)

Previous thyroid hormone replacement therapy

n (%)

37 (1.8)

Pre-operative complications

n (%)

13 (0.6)

 Dysphonia

 

5 (0.2)

 Neck pain

 

3 (0.1)

 Palpitations

 

3 (0.1)

Thyroid symptoms

n (%)

 

 Hoarseness

 

41 (2.0)

 Dysphagia

 

13 (0.6)

 Dyspnea

 

14 (0.7)

 Cervical mass

 

624 (31.0)

Preoperative evaluation

 Ultrasound

n (%)

1937 (96.2)

  Suspicious lymph node metastases

n (%)

633 (31.4)

  Benign

n (%)

608 (30.2)

  Malignant

n (%)

1348 (67.0)

  Unknown

n (%)

57 (2.8)

  Thyroid nodules present

n (%)

1937 (96.2)

  Number of nodules

Median (range)

2.0 (1–9)

  Nodule size, cm

Median (range)

0.97 (0.08–13.20)

 FNAB

n (%)

738 (36.7)

 Thyroid/neck lymph node abnormalities

n (%)

1427 (71.0)

 Baseline TSH available

n (%)

1927 (95.7)

 Baseline TSH value (mU/L)

Median (range)

2.21 (0.00–100.00)

Surgical approach

 Total/near-total thyroidectomy

n (%)

1672 (83.1)

 Lobectomy + isthmusectomy

n (%)

202 (10.0)

 Other types of thyroidectomy

n (%)

139 (6.9)

 Lymph node dissection

n (%)

1993 (99.0)

  Central (level VI, VII)

n (%)

1913 (95.0)

  Lateral (level I–V)

n (%)

880 (43.7)

  Therapeutic

n (%)

1279 (63.5)

  Prophylactic

n (%)

710 (35.2)

 TSH suppression

n (%)

1841 (91.5)

 RAI after surgery

n (%)

982 (48.8)

  1. FNAB fine needle aspiration biopsy, TSH thyroid-stimulating hormone, RAI radioactive iodine therapy