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Table 2 Association between glycohemoglobin (%) and HDL-C (mg/dL)

From: The relationship between high-density lipoprotein cholesterol (HDL-C) and glycosylated hemoglobin in diabetic patients aged 20 or above: a cross-sectional study

  Model 1, β(95% CI) , p Model 2, β(95% CI) , p Model 3, β(95% CI) , p P for interaction
HDL-C -0.008, (− 0.010, − 0.007), < 0.001 − 0.010,(− 0.012, − 0.008),< 0.001 − 0.004,(− 0.008, − 0.000),0.044  
Tertiles of HDL-C
 Lowest tertile Reference Reference Reference  
  Q2 −0.161, (− 0.237, − 0.085),<  0.001 −0.164,(− 0.236, − 0.091),< 0.001 −0.016,(− 0.042, − 0.003),0.006  
  Q3 −0.328, (− 0.403, − 0.252),< 0.001 − 0.382, (− 0.458, − 0.307), < 0.001 − 0.070,(− 0.210, − 0.017),0.033  
P for trend < 0.001 < 0.001 < 0.001  
Stratified by sex    0.923
 Male −0.010, (− 0.013, − 0.007),< 0.001 − 0.011,(− 0.014, − 0.008),< 0.001 − 0.009,(− 0.016, − 0.007), < 0.001  
 Female − 0.009,(− 0.011, − 0.006),< 0.001 − 0.010,(− 0.012, − 0.007),< 0.001 − 0.002,(− 0.007, 0.003), 0.551  
Stratified by race/ethnicity    0.027
 Mexican American −0.008, (− 0.015, − 0.001), 0.022 −0.013,(− 0.020, − 0.006),< 0.001 0.008,(− 0.005, 0.022),0.248  
 Other Race/ethnicity −0.011, (− 0.016, − 0.006), < 0.001 − 0.010,(− 0.015, − 0.004),< 0.001 − 0.005,(− 0.014, 0.004),0.307  
 Non-Hispanic White − 0.008, (− 0.011, − 0.006), < 0.001 −0.011, (− 0.013, − 0.008), < 0.001 −0.008,(− 0.014, − 0.001),0.025  
 Non-Hispanic Black −0.007,(− 0.012, − 0.002),0.004 −0.008,(− 0.013, − 0.004),< 0.001 −0.008,(− 0.017, 0.007), 0.054  
Stratified by age    0.023
 Age < 40 years −0.005,(− 0.008, − 0.003), < 0.001 −0.005, (− 0.008, − 0.003),< 0.001 −0.003(− 0.009,0.004)0.447  
 Age > =40, < 60 years −0.010,(− 0.014, − 0.007),< 0.001 −0.011,(− 0.014, − 0.007),< 0.001 −0.004(− 0.010,0.003)0.258  
 Age > =60 years − 0.014,(− 0.017, − 0.011),< 0.001 − 0.015, (− 0.018, − 0.012) < 0.001 − 0.008(− 0.017,0.001)0.092  
  1. Model 1: No adjustment for variables;
  2. Model 2: Sex, age, and race/ethnicity were adjusted;
  3. Model 3: Sex, age, race/ethnicity, BMI, waist circumference, systolic blood pressure, diastolic blood pressure, ALT, Cr, TG, TC, LDL, FDG, γGT, uric acid, insulin and lipid-lowering medications and anti-diabetic medications were adjusted.
  4. Sex, age, race/ethnicity, BMI, waist circumference, systolic blood pressure, diastolic blood pressure, ALT, Cr, TG, TC, LDL, FDG, γGT, uric acid, insulin and lipid-lowering medications and anti-diabetic medications were adjusted in the interaction analysis: