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Table 1 Clinical and laboratory characteristics of the study groups based on GnRH stimulation test results

From: Precocious puberty in Korean girls with and without exposure to endocrine-disrupting chemicals in toy slime: a comparative analysis

Characteristic

GnRH(+) (n = 58)

GnRH(-) (n = 82)

p value

CA(yr)

6.99 ± 0.82

7.08 ± 1.09

0.600

BA-CA(yr)

0.55 ± 1.22

0.95 ± 1.12

0.053

Tanner stage

3.33 ± 0.75

2.83 ± 0.56

< 0.05*

Height SDS

0.90 ± 1.54

1.28 ± 1.34

0.120

BMI z-score

0.50 ± 1.24

1.37 ± 1.58

< 0.05*

Basal LH(mIU/mL)

0.80 ± 3.47

0.08 ± 0.10

0.065

Peak LH(mIU/mL)

9.63 ± 9.25

2.38 ± 1.17

< 0.05*

Basal FSH(mIU/mL)

3.02 ± 1.60

1.77 ± 1.25

< 0.05*

Peak FSH(mIU/mL)

21.89 ± 7.69

14.32 ± 6.75

< 0.05*

Peak LH/Peak FSH

0.50 ± 0.48

0.19 ± 0.11

< 0.05*

Slime (EDCs) exposure(N, %)

14 (24.1 %)

65 (79.2 %)

< 0.05*

  1. GNRH gonadotropin-releasing hormone, CA chronological age, yr years, BA Bone age, BMI body mass index, LH Luteinizing hormone, FSH Follicle-stimulating hormone, N number, EDCs endocrine-disrupting chemicals
  2. *P value <0.05