Table 3 Comparison of biochemical remission and medical responsiveness among various pathological subtypes of GH-producing pituitary adenoma
Variables | Single Staining n = 48 (%67.6) | Dual Staining n = 23(%32.4) | Total n = 71(100%) | ||
|---|---|---|---|---|---|
Densely granulated n = 34 (%47.9) | Sparsely granulated n = 14 (%19.7) | Total n = 48 (%67.6) |  |  | |
Remission after surgery | |||||
 Total resection, n (%) | 25(73.5) | 6(42.9) | 31(64.6) | 13(56.5) | 44(62.0) |
 Biochemical remission, n (%) | 23(67.6) | 7(50.0) | 30(62.5) | 12(52.2) | 42(59.2) |
Responses to medications | |||||
 †Medication for remission, n (%) | 9(26.5) | 8(57.1) | 17(35.4) | 10(43.5) | 27(38.0) |
 Mean Sandostatine LAR dosages, mg (SD) | 23.3 ± 5* | 30 ± 5.8* | 26.2 ± 6.2 | 22.2 ± 4.4* | 24.6 ± 5.9 |
 Response to Sandostatine LAR, n (%) | |||||
  Full responder | 2(33.3) | 0(0) | 2(16.7) | 5(62.5) | 7(35.0) |
  Partial responder | 1(16.7) | 2(33.3) | 3(25.0) | 2(25.0) | 5(25.0) |
  Poor responder | 3(50.0) | 4(66.7) | 7(58.3) | 1(12.5) | 8(40.0) |
Recurrence††, n (%) | 0(0) * | 3(42.8) * | 3(10) | 2(16.6) * | 5(11.9) |
Resurgery, n (%) | 1(2.9) | 2(14.3) | 3(6.2) | 0(0) | 3(4.2) |
Radiation, n (%) | 2(5.9) | 3(21.4) | 5(10.4) | 0(0) | 5(7.0) |