Fig. 5
From: The genomic profiling and MAMLD1 expression in human and canines with Cushing’s disease
Immunohistochemistry for proteins suspected to be overexpressed in Cushing’s disease. Thirty one human corticotroph pituitary adenomas (PA) were sectioned, stained, and scored (0 to 3+). Respective 3+ PA and negative control normal are presented. POMC (26/31, 83.9%), MAMLD1 (22/31, 70.9%), USP8 (22/31, 70.9%), TBX19 (16/31 50.9%), USP48 (16/31, 50.9%) demonstrated strong (3+) staining. MNX1 (12/31, 38.7%) and RASEF (5/31, 16.2%) displayed less stronger (< 3) staining