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Fig. 2 | BMC Endocrine Disorders

Fig. 2

From: Thyroid-related ophthalmopathy development in concurrence with growth hormone administration

Fig. 2

Sequential change of thyroid-related ophthalmopathy demonstrated by magnetic resonance imaging. The clinical course of growth hormone and glucocorticoid therapy, symptoms of Graves’ ophthalmopathy, and points of MRI evaluations are displayed (A). The bilateral lachrymal glands swelling, especially in left side (B), and right eyelid swelling (C, D) indicating thyroid-related ophthalmopathy after growth hormone replacement are shown. Minimal attenuation of swellings in lachrymal glands is shown after growth hormone discontinuation (E), while edematous change in right eyelid persisted (F, G). Glucocorticoid therapies improve further bilateral lachrymal glans and right eyelid edema (H, I, J). (B, E, H): frontal section of T2 weighted image. (C, F, I): horizontal section of T2 weighted image (C: short T1 inversion recovery; F and I: iterative decomposition of water and fat with echo asymmetry and least squares estimation). (D, G, J): sagittal section image (D: T1 weighted image; G and J: fluid-attenuated inversion recovery). Arrows indicate bilateral lachrymal gland (B, E, H) and right eyelids (C, D, F, G, I, J). Arrowheads (G, J) indicate pituitary gland exhibiting a mild compression form

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