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Table 2 Correlations of the relative expressions of microRNA-29a and microRNA-122, serum sestrin 2, hsCRP, IL-6 and TNF-α levels with the studied anthropometric and metabolic parameters in whole study sample

From: Investigation of the levels of circulating miR-29a, miR-122, sestrin 2 and inflammatory markers in obese children with/without type 2 diabetes: a case control study

  WC percentile BMI percentile HDL-c (mg/dl) LDL-c (mg/dl) TAG (mg/dl) Cholesterol
(mg/ml)
HbA1c
(%)
Glucose (mg/dl) Insulin (μg/ml) C-Peptide (ng/ml) HOMA-IR hsCRP (mg/dl) IL-6 (pg/ml) TNF-α (pg/ml)
miR-29aR 0.478** 0.458** −0.315** 0.460** 0.517** 0.365** 0.570** 0.654** 0.356** 0.254** 0.651** 0.497** 0.267** 0.355**
miR-122R 0.610** 0.619** −0.457** 0.277** 0.384** 0.201 0.468** 0.412** 0.513** 0.293** 0.631** 0.502** 0.427** 0.453**
Sestrin2
(ng/ml)
−0.495** −0.844** 0.308* −0.215* −0.273** − 0.077 −0.428** − 0.321** −0.331** − 0.227** −0.558** − 0.577** −0.504** − 0.541**
hsCRP (mg/dl) 0.874** 0.815** −0.455** 0.231** 0.402** 0.277** 0.672** 0.578** 0.342** 0.366** 0.605** 1 0.521** 0.664**
IL-6 (pg/ml) 0.440** 0.411** −0.364** 0.271** 0.362** 0.271** 0.456** 0.481** 0.358** 0.319** 0.748**   1 0.626**
TNF-α (pg/ml) 0.529** 0.510** −0.456** 0.287** 0.508** 0.289** 0.613** 0.506** 0.469** 0.428** 0.679**    1
  1. The values presented in the table are for the correlation coefficient
  2. non-significant correlation
  3. *correlation is significant at 0.05
  4. **correlation is significant at 0.01
  5. WC: waist circumference, BMI: body mass index, HDL-c: high density lipoprotein cholesterol, LDL-c: low density lipoprotein cholesterol, TAG: triacylglycerol, HbA1c: glycosylated hemoglobin, HOMA-IR: Homeostatic model Assessment-Insulin resistance, miR-29a R: microRNA-29a relative expression, miR-122 R: microRNA-122 relative expression, hsCRP: high-sensitivity C-reactive protein, IL-6: interleukin 6, TNF-α: tumor necrosis factor alpha