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Table 1 Comparison of different variables among G1, G2 and G3

From: Investigation of the levels of circulating miR-29a, miR-122, sestrin 2 and inflammatory markers in obese children with/without type 2 diabetes: a case control study

  Healthy control group
(G1; n = 136)
Obese group
(G2; n = 90)
Obese with type 2 diabetes group
(G3; n = 72)
Gender
n (%)
Male 88 (64.7%) 62 (68.9%) 45 (62.5%) a, ¶
Female 48 (35.3%) 28 (31.1%) 27 (37.5%) a, ¶
Age (years) 12.1 ± 1.3 12.2 ± 1.4 12.2 ± 1.2
WC percentile 72.3 ± 7.2 95.9 ± 2.9 96.1 ± 2.9 *
BMI percentile 79.1 ± 6.8 96.8 ± 1.5 96.7 ± 1.4 *
HDL-c (mg/dl) 41.2 ± 2.9 35.7 ± 8.5 34.0 ± 9.5 *
LDL-c (mg/dl) 120.4 ± 21.4 126.1 ± 25.6 132.4 ± 17.0
TAG (mg/dl) 107.8 ± 19.6 112.7 ± 21.3 142.4 ± 37.1
Cholesterol (mg/dl) 183.2 ± 21.6 184.4 ± 26.6 194.9 ± 21.1
Glucose (mg/dl) 81.7 ± 12.7 96.8 ± 20.6 106.5 ± 25.7 #
HbA1c (%) 4.4 ± 0.7 6.0 ± 1.8 7.9 ± 1.9 #
Insulin (μg/ml) 7.6 ± 1.7 10.2 ± 0.7 10.6 ± 1.2*
C-Peptide (ng/ml) 2.8 ± 0.4 3.0 ± 0.3 3.1 ± 0.3
HOMA-IR 1.5 ± 0.4 2.4 ± 0.5 2.8 ± 0.6 #
miR-29a R 1.5 ± 0.3 1.9 ± 0.2 2.3 ± 0.3 #
miR-122 R 1.6 ± 0.3 1.9 ± 0.6 2.6 ± 0.9 #
Sestrin2 (ng/mL) 5.8 ± 1.8 4.1 ± 2.6 2.9 ± 1.4 #
hsCRP (mg/dl) 0.8 ± 0.1 1.3 ± 0.1 1.4 ± 0.2 #
IL-6 (pg/ml) 1.8 ± 0.4 2.2 ± 0.8 2.7 ± 1.1 #
TNF-α (pg/ml) 1.1 ± 0.2 1.3 ± 0.1 1.6 ± 0.6 #
  1. Unless otherwise indicated, the data is presented as mean ± Standard deviation
  2. WC: waist circumference, BMI: body mass index, HDL-c: high density lipoprotein cholesterol, LDL-c: low density lipoprotein cholesterol, TAG: triacylglycerol, HbA1c: glycosylated hemoglobin, HOMA-IR: Homeostatic model Assessment-Insulin resistance, miR-29a R: microRNA-29a relative expression, miR-122 R: microRNA-122 relative expression, hsCRP: high-sensitivity C-reactive protein, IL-6: interleukin 6, TNF-α: tumor necrosis factor alpha
  3. aChi-square
  4. the p-values of G1 Vs. G2 Vs. G3, G1 Vs. G2, G1 Vs. G3 and G2 Vs. G3 were non-significant
  5. * the p-values of G1 Vs. G2 Vs. G3, G1 Vs. G2, and G1 Vs. G3 were > 0.001 while G2 Vs. G3 were non-significant
  6. # the p-values of G1 Vs. G2 Vs. G3, G1 Vs. G2, G1 Vs. G3 and G2 Vs. G3 were > 0.001
  7. the p-values of G1 Vs. G2 Vs. G3, G1 Vs. G2, G1 Vs. G3 and G2 Vs. G3 were (0.01, 0.02, 0.009 and 0.44, respectively)
  8. The p-values of G1 Vs. G2 Vs. G3 for LDL-c (0.06), TAG (> 0.001) and Cholesterol (non-significant