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Table 3 Changes in the number of masses in all participants and in single and multiple fibroadenomas

From: Metformin as a new option in the medical management of breast fibroadenoma; a randomized clinical trial

 

Metformin Group

Placebo Group  

p-value

Single mass-total; n (%)

39 (100)

56 (100)

0.74

  Disappearance

4 (10.2)

7 (12.5)

  Without change

34 (87.2)

46 (82.1)

  Increased number

1 (2.6)

3 (5.4)

Multiple mass-total; n (%)

44 (100)

36 (100)

0.08

  Disappearance

6 (13.6)

3 (8.3)

  Without change or decreased 

34 (77.3)

23 (63.9)

  Increased number

4 (9.1)

10 (27.8)

In all cases; n (%)

83 (100)

92 (100)

0.21

  Disappearance

10 (12.1)

10 (10.9)

  Without change or decreased 

68 (81.9)

69 (75)

  Increased number

5 (6)

13 (14.1)

  1. P-value refers to Chi-square test.