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Table 1 Clinical characteristics of patients with Wolfram syndrome (DIDMOAD)

From: Unique three-site compound heterozygous mutation in the WFS1 gene in Wolfram syndrome

Case no. Age Sex DI, age at diagnosis DM, age at diagnosis OA, age at diagnosis HI, age at diagnosis Other features, age at diagnosis UCVA
1 18 M No Type 1, 9 years Bilateral, 16 years Left MF, 17 Years Abnormal MRI of brain, uroschesis OD: 0.04
OS: 0.1
2 14 M No Type 1, 9 years Bilateral, 11 years No Abnormal MRI of brain, uroschesis OD: 0.2
OS: 0.1
  1. DM diabetes mellitus, OA optic atrophy, DI diabetes insipidus, HI hearing impairment, MF medium-frequency hearing impairment, UCVA uncorrected visual acuity, EEG Electroence phalography, OD right eye, OS left eye