Fig. 2
From: Unique three-site compound heterozygous mutation in the WFS1 gene in Wolfram syndrome
Optic coherence tomography of two patients with WFS1 mutation. Optic coherence tomography (OCT) shows that peripapillary retinal nerve fiber layer (RNFL) thickness significantly decreases. The left graph shows the thickness of the retinal nerve fiber layer in both eyes of patient 1. The right graph shows retinal thickness in both eyes of patient 2. The red part represents a decrease in thickness less than 1% outside normal, and the green part indicates a decrease within the normal limit. Patient 2 represented in the right figure cannot be measured with standardized data because he is under 18 years of age. RNFL: retinal nerve fiber layer; OD: right eye; OS: left eye