Skip to main content

Table 2 Association of adiposity and cardiometabolic illness with Covid-19-related mortality

From: Increasing adiposity and the presence of cardiometabolic morbidity is associated with increased Covid-19-related mortality: results from the UK Biobank

  Total tested Positive swab Positive swab (died) Odds ratio [95% CI] P
Underweight (%) 1.53 1.57 3.27 1.62 [0.28–9.42] > 0.05a
Normal weight (%) 27.09 23.57 18.03 Reference
Overweight (%) 40.95 41.94 39.67 0.98 [0.67–1.43] > 0.05a
Obese I (%) 20.44 20.54 24.59 1.33 [0.87–2.01] > 0.05a
Obese II (%) 9.98 12.36 14.42 1.70 [1.06–2.74] < 0.05a
BMI (kg/m2) 28.26 ± 5.22 28.79 ± 5.39 29.66 ± 5.74 1.04 [1.01–1.07] < 0.001a
Waist:hip ratio (WHR) 0.89 ± 0.09 0.90 ± 0.09 0.93 ± 0.09 10.71 [1.57–73.06] < 0.05a
Body fat (%) 32.06 ± 8.66 32.13 ± 8.60 32.17 ± 8.86 1.03 [1.01–1.05] < 0.05a
CRP 3.01 ± 4.79 3.21 ± 5.83 3.88 ± 6.69 1.02 [1.00–1.04] > 0.05a
Hypertension (%) 36.21 35.45 54.75 2.68 < 0.001b
Dyslipidaemia (%) 19.03 19.03 29.18 2.05 < 0.001b
Atrial fibrillation (%) 8.44 8.48 15.08 2.36 < 0.001b
Ventricular arrhythmia (%) 0.84 0.55 0.98 2.22 > 0.05b
Diabetes (%) 12.05 14.12 22.95 2.16 < 0.001b
Stroke (%) 2.36 2.18 3.93 2.25 > 0.05b
Angina (%) 11.37 11.09 17.38 1.97 < 0.001b
  1. Referenced to the normal weight category, participants with a BMI in the highest obesity category (obese II) demonstrate a greater odds ratio of Covid-19-related mortality. Similarly, concurrent cardiometabolic morbidity was also associated with higher mortality. Obesity was also classified as a categorical variable based on BMI (underweight, BMI < 18.5 kg/m2; normal weight, 18.5 to < 25 kg/m2; overweight, 25 to < 30 kg/m2; obese I, 30 to < 35 kg/m2; and obese II, ≥ 35 kg/m2). Anthropometric and clinical indices were treated as continuous variables. Logistic regression model adjusted for age and sex was used to calculate odds ratios for continuous variables (a). Chi-squared test was used for categorical variables (b)