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Table 5 Interactions between CAV-1 rs3807992 and healthy dietary intake on CVDs risk factors

From: Interactions between Caveolin-1 (rs3807992) polymorphism and major dietary patterns on cardio-metabolic risk factors among obese and overweight women

 

β (95%CI) (AA + AG)

1(Ref) GG

 

Crude

P*

Adjusted

P**

TC (mg/dl)

−0.02 (−.07,0.03)

0.44

− 0.04 (−.09,0.006)

0.08

HDL-C (mg/dl)

6.67 (−.13,13.48)

0.05

7.74 (−0.76,14.72)

0.03

LDL-C (mg/dl)

7.68 (−7.43,22.81)

0.31

−2.53(−18.19,13.12)

0.75

TC/HDL

−0.86 (−1.81,0.08)

0.07

−1.01 (− 1.97,0.05)

0.03

LDL/HDL

−0.07 (−.44,0.29)

0.67

− 0.31 (−.67,0.04)

0.08

TG (mg/dl)

−0.09 (− 0.61,0.42)

0.72

−4.33 (−47.04,38.37)

0.84

ALT (IU.L)

−2.64(−11.06,5.7)

0.53

−3.38 (− 12.27,5.5)

0.45

AST (IU.L)

−0.95(−5.55,3.97)

0.74

−1.34 (−6.29,3.61)

0.59

hs-CRP (mg/L)

−0.38 (− 0.74, − 0.02)

0.03

−0.34 (− 0.68,-0.007)

0.04

MCP-1 (ng/ml)

−51.88 (− 112.93,9.17)

0.09

−60.89 (− 124.51,2.72)

0.06

PAI-1 (ng/ml)

−12.45 (− 34.91,10.01)

0.27

− 12.42(− 36.24,11.4)

0.30

IL1B (pg/ml)

− 0.16 (− 0.51,0.18)

0.35

− 0.33 (− 0.69,0.02)

0.06

  1. Values are represented as β (95%CI)
  2. A significant p-values are indicated in bold (significance considered p < 0.05)
  3. GLM was performed to identify significant differences between tertiles of healthy DP and CAV-1 rs3807992
  4. P* = with unadjusted (crude) model
  5. P** = with adjustments for potential confounding factors including (age, energy intake, physical activity, DBP)