Skip to main content

Table 5 Interactions between CAV-1 rs3807992 and healthy dietary intake on CVDs risk factors

From: Interactions between Caveolin-1 (rs3807992) polymorphism and major dietary patterns on cardio-metabolic risk factors among obese and overweight women

  β (95%CI) (AA + AG)
1(Ref) GG
 
Crude P* Adjusted P**
TC (mg/dl) −0.02 (−.07,0.03) 0.44 − 0.04 (−.09,0.006) 0.08
HDL-C (mg/dl) 6.67 (−.13,13.48) 0.05 7.74 (−0.76,14.72) 0.03
LDL-C (mg/dl) 7.68 (−7.43,22.81) 0.31 −2.53(−18.19,13.12) 0.75
TC/HDL −0.86 (−1.81,0.08) 0.07 −1.01 (− 1.97,0.05) 0.03
LDL/HDL −0.07 (−.44,0.29) 0.67 − 0.31 (−.67,0.04) 0.08
TG (mg/dl) −0.09 (− 0.61,0.42) 0.72 −4.33 (−47.04,38.37) 0.84
ALT (IU.L) −2.64(−11.06,5.7) 0.53 −3.38 (− 12.27,5.5) 0.45
AST (IU.L) −0.95(−5.55,3.97) 0.74 −1.34 (−6.29,3.61) 0.59
hs-CRP (mg/L) −0.38 (− 0.74, − 0.02) 0.03 −0.34 (− 0.68,-0.007) 0.04
MCP-1 (ng/ml) −51.88 (− 112.93,9.17) 0.09 −60.89 (− 124.51,2.72) 0.06
PAI-1 (ng/ml) −12.45 (− 34.91,10.01) 0.27 − 12.42(− 36.24,11.4) 0.30
IL1B (pg/ml) − 0.16 (− 0.51,0.18) 0.35 − 0.33 (− 0.69,0.02) 0.06
  1. Values are represented as β (95%CI)
  2. A significant p-values are indicated in bold (significance considered p < 0.05)
  3. GLM was performed to identify significant differences between tertiles of healthy DP and CAV-1 rs3807992
  4. P* = with unadjusted (crude) model
  5. P** = with adjustments for potential confounding factors including (age, energy intake, physical activity, DBP)