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Table 2 The association between metabolic markers and the genotypes of Cav-1 rs3807992 polymorphism

From: Interactions between Caveolin-1 (rs3807992) polymorphism and major dietary patterns on cardio-metabolic risk factors among obese and overweight women

 

CAV-1 (rs3807992)

P value*

P-value**

GG

(AG + AA)

Age(year)

37.56 ± 9.49

35.75 ± 8.78

0.05

 

BMI

30.68 ± 4.01

31.66 ± 4.46

0.02

 

TC(mg/dl)

186.76 ± 33.74

182.71 ± 37.36

0.30

0.04

HDL-C(mg/dl)

49.07 ± 11.16

44.04 ± 10.16

< 0.0001

0.003

LDL-C(mg/dl)

98.80 ± 22.66

91.27 ± 25.07

0.006

0.001

LDL.HDL

2.07 ± 0.53

2.14 ± 0.64

0.58

0.56

TC.HDL

3.93 ± 0.89

4.43 ± 1.91

0.01

0.23

TG(mg/dl)

113.11 ± 51.20

133.31 ± 84.14

0.13

0.14

ALT (IU.L)

18.27 ± 7.44

17.95 ± 8.29

0.41

0.24

AST(IU.L)

19.04 ± 13.95

20.14 ± 14.19

0.61

0.88

hs-CRP(mg/L)

4.18 ± 4.40

4.33 ± 4.76

0.94

0.68

MCP-1(ng/ml)

51.49 ± 102.26

48.42 ± 81.14

0.8

0.99

PAI.1(ng/ml)

19.24 ± 38.43

12.70 ± 17.42

0.16

0.94

IL1B(pg/ml)

0.36 ± 0.54

0.37 ± 0.53

0.94

0.95

  1. SD Standard deviation; BMI Body mass index; TC Total cholesterol; HDL High density lipoprotein; LDL Low density lipoprotein; TG Triglyceride; ALT Alanine aminotransferase; AST Aspartate aminotransferase; hs-CRP High-sensitivity C-reactive protein; MCP-1 monocyte chemoattractant protein; PAI-1 Plasminogen Activator Inhibitor 1; IL1B Interleukin 1 beta
  2. * P-value for crude model
  3. **P value for adjusted model (BMI considered as collinear and this variable adjusted for Age, physical activity level, energy intake)