Table 2 Comparison between new-diagnosed young-onset and adult-onset patients with T1D
From: Clinical and demographic features among patients with type 1 diabetes mellitus in Henan, China
|  | Young-onset (n = 234) | Adult-onset (n = 219) | P-value |
|---|---|---|---|
Male (%) | 120(51.3) | 141(64.4) | 0.006 |
Age at diagnosis(year) | 11(7,13) | 28(24,37) | < 0.001 |
HbA1c (%) | 12.9 ± 2.4 | 11.7 ± 3.0 | < 0.001 |
HbA1c(mmol/mol) | 117 ± 3 | 104 ± 9 | < 0.001 |
Diabetic ketoacidosis at onset | 148(64.5) | 91(43.5) | < 0.001 |
Overweight or Obesity | 12(9.5) | 32(24.6) | 0.002 |
Overweight | 6(4.8) | 23(17.7) | 0.001 |
Obesity | 6(4.8) | 9(6.9) | 0.597 |
Glutamic acid decarboxylase antibody | 49(23.3) | 61(33.7) | 0.025 |
Islet-cell antibodies | 43(20.6) | 46(25.4) | 0.277 |
Insulin antibodies | 7(3.3) | 3(1.7) | 0.351 |
Dyslipidemia | 98(51.3) | 106(58.2) | 0.212 |
High total cholesterol | 31(16.6) | 16(8.8) | 0.029 |
High triglyceride | 36(18.8) | 28(15.4) | 0.412 |
Low high-density lipoprotein cholesterol | 82(42.9) | 92(51.4) | 0.118 |
High low-density lipoprotein cholesterol | 14(7.4) | 17(9.5) | 0.574 |
Urine acetone bodies | 177(77.0) | 151(71.9) | 0.230 |
Proteinuria | 32(14.0) | 28(13.4) | 0.890 |
Diabetes family history | 50(21.5) | 51(23.4) | 0.652 |
Fasting plasma glucose (mmol/l) | 6.6 (5.2,8.0) | 7.3 (5.6,10.0) | 0.051 |
Fasting C-peptide (ng/ml) | 0.3 (0.2,0.5) | 0.4 (0.2,0.7) | < 0.001 |
2-h C-peptide (ng/ml) | 0.7 (0.4,1.1) | 0. 9 (0.6,1.8) | < 0.001 |
Total cholesterol (mmol/l) | 4.0 (3.4,4.9) | 4.1 (3.3,4.8) | 0.785 |
Triglyceride (mmol/l) | 1.0 (0.7, 1.6) | 1.2 (0.8,1.9) | 0.347 |
High-density lipoprotein cholesterol (mmol/l) | 1.1 (0.9,1.4) | 1.0 (0.9,1.2) | 0.006 |
Low-density lipoprotein cholesterol (mmol/l) | 2.3 (1.9,2.9) | 2.5(2.0,3.3) | 0.057 |
Undetectable/ detectable C-peptide | 5/179 | 19/166 | 0.003 |