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Table 2 Comparison between new-diagnosed young-onset and adult-onset patients with T1D

From: Clinical and demographic features among patients with type 1 diabetes mellitus in Henan, China

  Young-onset
(n = 234)
Adult-onset
(n = 219)
P-value
Male (%) 120(51.3) 141(64.4) 0.006
Age at
diagnosis(year)
11(7,13) 28(24,37) < 0.001
HbA1c (%) 12.9 ± 2.4 11.7 ± 3.0 < 0.001
HbA1c(mmol/mol) 117 ± 3 104 ± 9 < 0.001
Diabetic ketoacidosis at onset 148(64.5) 91(43.5) < 0.001
Overweight or Obesity 12(9.5) 32(24.6) 0.002
Overweight 6(4.8) 23(17.7) 0.001
Obesity 6(4.8) 9(6.9) 0.597
Glutamic acid decarboxylase antibody 49(23.3) 61(33.7) 0.025
Islet-cell antibodies 43(20.6) 46(25.4) 0.277
Insulin antibodies 7(3.3) 3(1.7) 0.351
Dyslipidemia 98(51.3) 106(58.2) 0.212
High total cholesterol 31(16.6) 16(8.8) 0.029
High triglyceride 36(18.8) 28(15.4) 0.412
Low high-density lipoprotein cholesterol 82(42.9) 92(51.4) 0.118
High low-density lipoprotein cholesterol 14(7.4) 17(9.5) 0.574
Urine acetone bodies 177(77.0) 151(71.9) 0.230
Proteinuria 32(14.0) 28(13.4) 0.890
Diabetes family history 50(21.5) 51(23.4) 0.652
Fasting plasma glucose (mmol/l) 6.6 (5.2,8.0) 7.3 (5.6,10.0) 0.051
Fasting C-peptide (ng/ml) 0.3 (0.2,0.5) 0.4 (0.2,0.7) < 0.001
2-h C-peptide (ng/ml) 0.7 (0.4,1.1) 0. 9 (0.6,1.8) < 0.001
Total cholesterol (mmol/l) 4.0 (3.4,4.9) 4.1 (3.3,4.8) 0.785
Triglyceride (mmol/l) 1.0 (0.7, 1.6) 1.2 (0.8,1.9) 0.347
High-density lipoprotein cholesterol (mmol/l) 1.1 (0.9,1.4) 1.0 (0.9,1.2) 0.006
Low-density lipoprotein cholesterol (mmol/l) 2.3 (1.9,2.9) 2.5(2.0,3.3) 0.057
Undetectable/ detectable C-peptide 5/179 19/166 0.003
  1. Comments: Values were presented as numbers of patients(percentages), median (interquartile range), or means ± SD