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Table 2 Baseline Characteristics of patients with PA discharged from the West China Hospital, 2009–2018

From: Developing a research database of primary aldosteronism: rationale and baseline characteristics

Characteristics Patients with PA diagnosis
N = 862
Patients with at least one positive confirmatory test of PA
N = 507
Age (yr), mean (SD) 47.8 (11.9) 49.2 (11.8)
  ≤ 45 yr, n (%) 367 (42.6) 182 (35.9)
 46-64 yr, n (%) 409 (47.2) 271 (53.5)
  > =65 yr, n (%) 85 (9.9) 54 (10.7)
Gender (male), n (%) 368 (42.7) 213 (42.0)
Race
 Han 846 (98.1) 493 (97.2)
 Other 16 (1.9) 14 (2.8)
BMI (kg/m2), mean (SD) 24.37 (8.4) 24.72 (3.7)
Comorbidities, n (%)
 CKD 48 (5.5) 37 (7.3)
 CAD 21 (2.4) 13 (2.6)
 DM 118 (13.7) 95 (18.7)
 OSA 75 (8.7) 75 (14.8)
Systolic Blood Pressure (mmHg) 156.1 (21.7) 155.8 (20.9)
  < 140 187 (21.7) 123 (24.3)
 140–159 294 (34.1) 173 (34.1)
 160–179 242 (28.1) 138 (27.2)
  ≥ 180 122 (14.2) 70 (13.8)
Diastolic Blood Pressure (mmHg) 97.2 (14.53) 96.2 (13.5)
  < 90 266 (30.9) 166 (32.7)
 90–99 209 (24.2) 144 (28.4)
 100–109 194 (22.5) 103 (20.3)
  ≥ 110 177 (20.5) 91 (17.9)
Serum Creatinine (umol/L) 76.0 (62.0, 90.0)a 74.6 (61.0, 89.0)a
HbA1C (%) 5.7 (5.2, 6.4)a 5.7 (5.3, 6.5)a
Serum Potassium (mmol/L) 2.85 (2.47, 3.36)a 2.93 (2.53, 3.42)a
Serum Aldosterone (ng/dL) 28.1 (20.0, 40.4)a 26.4 (20.3, 36.5)a
ARR (ng/dL)/(ng/ml·h) 153.5 (102.8, 277.3)a 161.4 (64.3, 353.4)a
PRA (ng/ml/h) 0.49 (0.22, 1.04)a 0.42 (0.16, 0.88) a
  1. CKD chronic kidney disease, CAD coronary artery disease, DM diabetes mellitus, OSA obstructive sleep apnea-hypopnea syndrome, BMI body mass index, ARR Aldosterone-to-Renin Ratio, PRA plasma renin activity
  2. a reported as median (25th – 75th percentile IQR)