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Table 1 Baseline characteristics of normal subjects and non-diabetic first degree relatives of Type 2 DM patients

From: Impact of triglycerides and waist circumference on insulin resistance and β-cell function in non-diabetic first-degree relatives of type 2 diabetes

  Normal subjects
(n = 39)
FDRs of Type 2 DM
(n = 64)
p-value
Age (years) 31.4 ± 4.61 32.3 ± 5.16 0.373
Body mass index (kg/m2) 21.2 ± 2.52 22.9 ± 2.11 0.0004
Waist Circumference (cm) 80.9 ± 7.94 88.4 ± 9.2 2.4 × 10−5
Systolic blood pressure (mmHg) 112 ± 11 117 ± 11 0.038
Diastolic blood pressure (mmHg) 73 ± 8 77 ± 8 0.009
Triglycerides (mmol/l) 1.31 ± 0.53 1.98 ± 0.76 8.6 × 10−7
HDL-cholesterol (mmol/l) 1.15 ± 0.22 1.08 ± 0.19 0.089
Fasting blood glucose (mmol/l) 4.99 ± 0.34 5.19 ± 0.47 0.026
Glycated hemoglobin (%) 5.0 ± 0.20 5.3 ± 0.28 4.9 × 10−9
Fructosamine (mmol/l) 248 ± 39.0 296 ± 41.6 6.0 × 10−8
Insulin (pmol/l) 38 ± 13.70 71.1 ± 28.60 6.6 × 10−12
HOMA-IR 0.8 ± 0.26 1.5 ± 0.60 5.5 × 10−12
HOMA-β 85 ± 24 117 ± 33 1.3 × 10−7
  1. Data are presented as means ± SD. Mean significant difference p < 0.05 bolded
  2. HOMA-IR insulin resistance, HOMA-β β-cell function