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Table 1 Clinical characteristics of patients with diabetic nephropathy and healthy controls

From: LncRNA HCP5 knockdown inhibits high glucose-induced excessive proliferation, fibrosis and inflammation of human glomerular mesangial cells by regulating the miR-93-5p/HMGA2 axis

Characteristic Normal DN
Male/female (number)
 Male 15 18
 Female 13 10
 Age (y) 51.3 ± 5.2 50.7 ± 7.8
 BMI (kg/m2) 22.8 ± 2.8 24.2 ± 3.7
 SBP (mm Hg) 109.9 ± 15.3 156.2 ± 27.7*
 DBP (mm Hg) 80.1 ± 6.8 85.8 ± 10.2*
 FPG (mM) 4.9 ± 2.2 8.3 ± 2.3*
 HbA1c (%) 5.2 ± 1.8 8.2 ± 2.1*
 TC (mM) 4.98 ± 1.2 6.13 ± 1.5*
 TG (mM) 1.26 ± 1.1 2.36 ± 1.21*
 LDL-C (mM) 3.05 ± 1.12 3.68 ± 1.16*
 BUN (mM) 5.19 ± 1.32 8.26 ± 1.41*
 SCr (μM) 60.18 ± 11.35 121.08 ± 20.23*
  1. Abbreviations: BMI, body mass index; BUN, blood urea nitrogen; DBP, diastolic blood pressure; DN, diabetic nephropathy; FPG, fasting plasma glucose; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; SCr, serum creatinine; TC, total cholesterol; TG, triglycerides. Unless indicated otherwise, data are given as the mean ± SD. *P < 0.05