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Table 3 Association between glycated hemoglobin A1c concentrations and the prevalence of TB

From: The association of glycemic level and prevalence of tuberculosis: a meta-analysis

Study Type of study Populations TB Non-TB P
Exposure n Mean ± SD/Median [IQR] Exposure n Mean ± SD/Median [IQR]  
Chan 2019 A cross–sectional study DM (n = 4209) HbA1c (%) 8 Mean ± SD: 9.1 ± 2.2 HbA1c (%) 4201 Mean ± SD: 7.7 ± 1.9 Not shown
Khalil 2016 Case-control study DM (n = 80) HbA1c (%) 80 Mean ± SD: 9.88 ± 2.03 HbA1c (%) 80 Mean ± SD: 7.89 ± 1.58 < 0.01
Kumpatla 2013 A cross–sectional study DM (n = 6967) HbA1c (%) 47 Mean ± SD: 9.2 ± 2.1 HbA1c (%) 6920 Mean ± SD: 8.5 ± 2.1 0.03
Leal 2019 Case-control study DM (n = 135) HbA1c (%) 22 Mean ± SD: 9.43 ± 2.06 HbA1c (%) 85 Mean ± SD: 7.86 ± 1.83 0.002
Sanchez-Jimenez 2018 A cross–sectional study DM (n = 50) HbA1c (%) 25 Mean ± SD: 7.8 ± 1.9 HbA1c (%) 25 Mean ± SD: 8.8 ± 2.4 Not shown
Webb 2009 A cross–sectional study DM (n = 258) HbA1c (%) 25 Mean ± SD: 13.3 ± 2.4 HbA1c (%) 233 Mean ± SD: 10.6 ± 2.4 0.001
Widjaja 2018 Case-control study DM (n = 80) HbA1c (%) 40 Mean ± SD: 8.78 ± 2.85 HbA1c (%) 40 Mean ± SD: 7.82 ± 1.75 0.19
Hensel 2016 A cross–sectional study Non-DM (n = 406), Pre-DM (n = 235), DM (n = 54) HbA1c (%) 221 Median [IQR]: 5.7 [5.4–6.0] HbA1c (%) 473 Median [IQR]: 5.5 [5.3–5.8] < 0.01
Martinez-Aguilar 2015 A cross–sectional study DM (n = 600) HbA1c (%) 308 Median [IQR]: 7.5 [6.5–8.5] HbA1c (%) 292 Median [IQR]:7.6 [6.8–8.7] 0.21
Marupuru 2017 Case–control study DM (n = 451) HbA1c (%) 152 Median [IQR]: 9.3 [7.5–11.6] HbA1c (%) 299 Median [IQR]: 7.9 [6.8–10.7] Not shown
  1. Abbreviation: DM: Diabetes mellitus, HbA1c: glycated hemoglobin A1c, IQR: interquartile range, SD: standard deviation, TB: Tuberculosis