Skip to main content

Table 4 Comparison of parameters between the first and second half of the study period

From: Post-operative volumes following endoscopic surgery for non-functioning pituitary macroadenomas are predictive of further intervention, but not endocrine outcomes

Characteristic Study period p-value
2009–2013 2014–2018
Patients (n = 159) 48 111  
Preoperative tumour volume (median, cm3) 5.51 (IQR: 2.84–9.56) 5.51 (IQR: 3.56–9.27) 0.75
Postoperative residual tumour volume (median, cm3) 1.28 (IQR: 0.61–2.19) 0.77 (IQR: 0.39–1.72) 0.01*
EOR (median, %) 78.3 (IQR: 63.5–84.2) 86.4 (IQR: 70.4–93.8) 0.005**
Endocrine Outcomes (n = 101)a
 • Preserved function 23/34 (67.6%) 37/67 (56.7%) 0.29
 • New hormone deficit(s) 8/34 (23.5%) 17/67 (25.4%) 0.99
 • Axis recovery 3/34 (8.8%) 13/67 (19.4%) 0.25
  1. aComplete endocrine data pre- and post-TSS was available in 101 patients (34 of whom were in the first half, 2009–2013 and 67 in the second half, 2014–2018)