Preoperative tumour volume | Males (n = 62) | Females (n = 39) | p-value |
 Mean tumour size (cm3) ± SD | 8.88 ± 8.56 | 6.46 ± 5.05 | 0.12 |
 Age at surgery (years) | 59.3 ± 13.3 | 0.35 | |
 Individual hormone axis | Mean tumour size (cm3) | p-value | |
  • GH deficiency | 8.45 ± 6.10 | 0.44 | |
  • LH/FSH deficiency | 8.81 ± 8.92 | 0.22 | |
  • ACTH deficiency | 7.17 ± 5.34 | 0.45 | |
  • TSH deficiency | 7.88 ± 6.41 | 0.93 | |
Number of pituitary hormone deficiencies | |||
 • 0 | 6.28 ± 4.18 | 0.69 | |
 • 1–2 | 9.00 ± 9.88 | ||
 • ≥3 | 7.92 ± 5.91 | ||
Postoperative Tumour Residuum | |||
 Mean tumour residuum size (cm3) ± SD | 1.96 ± 4.46 | ||
 Number of pituitary hormone deficiencies | Mean tumour size (cm3) | p-value | |
  • 0 | 1.68 ± 2.29 | 0.44 | |
  • 1–2 | 2.34 ± 6.39 | ||
  • ≥ 3 | 1.24 ± 2.07 | ||
 Extent of Resection (EOR) | |||
  Mean EOR (%) ± SD | 75.9 ± 21.8; Range: 3.4–100% | ||
  Gross total resection (GTR) | 7 (6.9%) | ||
  Near total resection (≥90 % ) | 28 (27.7%), including 7 GTR | ||
  Subtotal resection (75–89.9%) | 39 (38.6%) | ||
  Partial resection (< 75%) | 30 (29.7%) | ||
 Endocrine outcomes | Mean EOR (%) ± SD | p-value | |
  • New axis deficit (n = 25) | 78.6 ± 23.5 | 0.48 | |
  • Axis recovery (n = 16) | 79.9 ± 16.9 | 0.45 | |
  • Pituitary function preserved (n = 60) | 73.8 ± 22.1 | 0.38 |