Table 1 Patient clinical manifestation stratified according to lactate level
From: Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit
Variables | Lactate > 2mmol/L (n = 61) | Lactate ≤ 2mmol/L (n = 46) | p | z/t/χ 2 |
|---|---|---|---|---|
Age (years) | 11(8.500, 14) | 8(4, 11) | < 0.001 | -3.625 |
Female (%) | 38(62.295 %) | 27(58.696 %) | 0.706 | 0.142 |
infection | 28(45.902 %) | 23(50 %) | 0.674 | 0.177 |
new onset diabetes mellitus (%) | 39(63.934 %) | 39(84.783 %) | 0.016 | 5.769 |
Family history of diabetes mellitus (%) | 6(9.836 %) | 9(19.565 %) | 0.151 | 2.059 |
Heart rate (beats/minute) | 133.508(5.375) | 120.543(19.873) | < 0.001 | 3.806 |
Systolic blood pressure(mmHg) | 114.183(20.340) | 110.565(17.735) | 0.340 | 0.959 |
Diastolic blood pressure(mmHg) | 73(56.500, 81) | 66(57.75, 74) | 0.028 | -2.191 |
PH | 7.025(0.148) | 7.098(0.167) | 0.020 | 2.368 |
Leukocyte count(109/L) | 18.41(12.990, 32.285) | 13.295(7.978, 23.463) | 0.004 | -2.898 |
C reactive protein(mg/L) | 8.13(4.435, 26.570) | 4.765(1.775, 11.955) | 0.167 | -1.381 |
Procalcitonin (ng/mL) | 1.11(0.235, 8.058) | 0.13(0.085, 1.455) | < 0.001 | -3.744 |
Creatinine (umol/L) | 44(34.625, 64.300) | 30.1(23.875, 38.625) | < 0.001 | -4.153 |
Blood urea nitrogen (mmol/L) | 5.905(3.473, 10.388) | 4.005(2.370, 5.653) | 0.002 | -3.037 |
Alanine transaminase (U/L) | 13.3(9.650, 19.75) | 11.1(8.425, 15.65) | 0.107 | -1.611 |
Triglycerides (mmol/L) | 1.82(1.185, 2.968) | 1.69(1.045, 3.32) | 0.336 | -0.962 |
Ferritin (ug/L) | 180.8(120.950, 322.725) | 153(83.825, 222.975) | 0.105 | -1.622 |
Blood glucose (mmol/L) | 27.8(19.050, 29) | 20.85(16.35, 27.35) | 0.002 | -3.05 |
C peptide (nmol/L) | 0.060(0.010, 0.155) | 0.135(0.09, 0.23) | 0.003 | -2.99 |
Glycosylated hemoglobin (%) | 12.485(2.591) | 12.917(2.347) | 0.377 | -0.887 |
Lactic dehydrogenase (U/L) | 289.5(217.75, 392.75) | 258(209, 336) | 0.144 | -1.46 |
Stage of severity | 0.044 | 6.246 | ||
Mild stage | 2 | 8 | ||
Moderate stage | 14 | 10 | ||
Severe stage | 45 | 28 |