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Table 3 Results of crude and adjusted logistic regression analysis of infertility by thyroid function and TPOAb status

From: The association between subclinical hypothyroidism and TPOAb positivity with infertility in a population-based study: Tehran thyroid study (TTS)

Female Male
Crude models
  *OR of infertility (95%CI) P_value *OR of infertility (95%CI) P_value
 FT4 (ng/dl) 0.997 (0.602–1.650) 0.991 0.189 (0.056, 0.637) * 0.007
 TSH (mU/L) 1.015 (0.976–1.054) 0.458 1.028 (1.001, 1.055) * 0.042
 TPOAb (IU/ml) 0.999 (0.998–1.000) 0.222 1.00 (0.996, 1.003) 0.833
 TPOAb Positive 1.0 (0.8,1.35) 0.953 0.7 (0.3,1. 5) 0.392
Negative (ref)   (ref)  
Age-and-BMI-Adjusted models
 FT4 (ng/dl) 1.003 (0.600–1.676) 0.991 0.280 (0.081, 0,967) * 0.044
 TSH (mU/L) 1.012 (0.974–1.052) 0.536 1.025 (0.998, 1.052) 0.070
 TPOAb (IU/ml) 0.999 (0. 998–1.000) 0.194 1.00 (0.996, 1.003) 0.874
 TPOAb Positive 0.97 (0.7,1.35) 0.888 0.7 (0.3,1.6) 0.416
Negative (ref)   (ref)  
ΨMulti-Adjusted models
 FT4 (ng/dl) 1.007 (0.596–1.702) 0.978 0.265 (0.075, 0.940) * 0.040
 TSH (mU/L) 1.012 (0.973–1.052) 0.552 1.026 (0.999, 1.053) 0.061
 TPOAb (IU/ml) 0.999 (0.998–1.000) 0.196 1.00 (0. 997, 1.003) 0.915
 TPOAb Positive 0.983 (0.694–1.393) 0.924 0.778 (0.304,1.992) 0.610
Negative (ref)   (ref)  
  1. *significant p-value < 0.05
  2. ΨAdjusted by Age, education, BMI, Smoking, Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Fasting blood Sugar (FBS)