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Table 3 Sensitivity and specificity of various parameters

From: Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas

Diagnostic criteria N Sensitivity Specificity
PAC > 171 ng/dL 32/141 26.7%(17.8–37.4) 84.3%(71.2–92.2)
Serum potassium< 3.5 mmol/L 54/141 36.7%(26.8–47.5) 58.8%(44.2–72.4)
Post-CCT/SIT ARR > 10(ng/dL)/(mU/L) 15/108 22.1%(12.9–33.8) 100%(93.2–100.0)
Hypertension; Serum potassium< 3.5 mmol/L;Post-CCT/SIT ARR > 10(ng/dL)/(mU/L) 9/108 13.0%(6.1–23.3) 100%(91.0–100.0)
Serum potassium< 3.5 mmol/L
or Post-CCT/SIT ARR > 10(ng/dL)/(mU/L)
51/108 49.3%(37.0–61.6) 56.4%(39.6–72.2)
  1. The data are expressed as n(%) unless noted otherwise;
  2. Abbreviations: CCT captopril challenge test, SIT saline infusion test, ARR ratio of aldosterone/renin, PAC plasma aldosterone concentration