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Table 3 Sensitivity and specificity of various parameters

From: Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas

Diagnostic criteria

N

Sensitivity

Specificity

PAC > 171 ng/dL

32/141

26.7%(17.8–37.4)

84.3%(71.2–92.2)

Serum potassium< 3.5 mmol/L

54/141

36.7%(26.8–47.5)

58.8%(44.2–72.4)

Post-CCT/SIT ARR > 10(ng/dL)/(mU/L)

15/108

22.1%(12.9–33.8)

100%(93.2–100.0)

Hypertension; Serum potassium< 3.5 mmol/L;Post-CCT/SIT ARR > 10(ng/dL)/(mU/L)

9/108

13.0%(6.1–23.3)

100%(91.0–100.0)

Serum potassium< 3.5 mmol/L

or Post-CCT/SIT ARR > 10(ng/dL)/(mU/L)

51/108

49.3%(37.0–61.6)

56.4%(39.6–72.2)

  1. The data are expressed as n(%) unless noted otherwise;
  2. Abbreviations: CCT captopril challenge test, SIT saline infusion test, ARR ratio of aldosterone/renin, PAC plasma aldosterone concentration