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Table 1 Baseline characteristics of included patients

From: Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas

Variable Lateralized
N = 90
Non-lateralized
N = 51
P value
Lateralization index 12.1 ± 28.0 1.5 ± 0.4 < 0.001
Mean Age 49.2 ± 10.3 50.0 ± 10.0 0.88
Sex, M/F(n%) 44 (48.9%)/46 (52.2%) 22 (43.1%)/29 (56.9%) 0.51
BMI (Kg/m2) 25.9 ± 2.7 25.2 ± 3.7 0.07
Systolic BP (mmHg) 145 ± 19 144 ± 21 0.32
Diastolic BP (mmHg) 91 ± 13 90 ± 15 0.24
Serum potassium (mmol/L) 3.6 ± 0.5 3.7 ± 0.5 0.98
Serum sodium (mmol/L) 137.1 ± 21.1 140.1 ± 2.1 0.07
Urinary potassium (mmol/d) 40.1 ± 15.9 37.8 ± 14.5 0.64
Urinary sodium (mmol/d) 181.5 ± 108.8 168.8 ± 97.8 0.75
Recumbent PAC (ng/dL) 11.9 [8.9–18.1] 11.1 [8.4–16.5] 0.70
Recumbent DRC (mU/L) 1.6 [0.9–5.0] 2.9 [1.3–5.6] 0.07
Recumbent ARR (ng/dL)/(mU/L) 4.8 [1.9–8.9] 3.1 [1.7–5.9] 0.19
Post-CCT/SIT ARR (ng/dL)/(mU/L) 2.9 [1.05–6.90] 2.2 [1.0–4.0] 0.24
ACR (mg/mmol) 118.7.1 ± 428.2 44.2 ± 76.5 0.09
Serum creatine (umol/L) 68.7 ± 23.5 70.4 ± 48.5 0.24
eGFR (ml/min/1.73 m2) 131.7 ± 41.0 137.0 ± 33.2 0.21
Hypertensive heart disease, n(%) 6 (8.8%) 2 (5.1%) 0.32
Ischemic heart disease, n(%) 31 (44.9%) 13 (33.3%) 0.71
Hypertensive Nephropathy,n(%) 26 (42.6%) 10 (27.8%) 0.31
Peripheral vascular disease, n(%) 11 (16.7%) 2 (5.1%) 0.19
Cerebrovascular disease, n(%) 27 (50.0%) 18 (51.4%) 0.13
Metabolic syndrome, n(%) 6 (8.8%) 2 (5.1%) 1.0
  1. Continuous variables are expressed as the mean ± SD or the medians [interquartile range] unless noted otherwise
  2. Abbreviations: LI Lateralization index, BMI body mass index, CCT captopril challenge test, SIT saline infusion test, ARR ratio of aldosterone/renin, PAC plasma aldosterone concentration, DRC direct renin concentration, ACR urinary albumin/creatinine ratio