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Table 1 Baseline characteristics of included patients

From: Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas

Variable

Lateralized

N = 90

Non-lateralized

N = 51

P value

Lateralization index

12.1 ± 28.0

1.5 ± 0.4

< 0.001

Mean Age

49.2 ± 10.3

50.0 ± 10.0

0.88

Sex, M/F(n%)

44 (48.9%)/46 (52.2%)

22 (43.1%)/29 (56.9%)

0.51

BMI (Kg/m2)

25.9 ± 2.7

25.2 ± 3.7

0.07

Systolic BP (mmHg)

145 ± 19

144 ± 21

0.32

Diastolic BP (mmHg)

91 ± 13

90 ± 15

0.24

Serum potassium (mmol/L)

3.6 ± 0.5

3.7 ± 0.5

0.98

Serum sodium (mmol/L)

137.1 ± 21.1

140.1 ± 2.1

0.07

Urinary potassium (mmol/d)

40.1 ± 15.9

37.8 ± 14.5

0.64

Urinary sodium (mmol/d)

181.5 ± 108.8

168.8 ± 97.8

0.75

Recumbent PAC (ng/dL)

11.9 [8.9–18.1]

11.1 [8.4–16.5]

0.70

Recumbent DRC (mU/L)

1.6 [0.9–5.0]

2.9 [1.3–5.6]

0.07

Recumbent ARR (ng/dL)/(mU/L)

4.8 [1.9–8.9]

3.1 [1.7–5.9]

0.19

Post-CCT/SIT ARR (ng/dL)/(mU/L)

2.9 [1.05–6.90]

2.2 [1.0–4.0]

0.24

ACR (mg/mmol)

118.7.1 ± 428.2

44.2 ± 76.5

0.09

Serum creatine (umol/L)

68.7 ± 23.5

70.4 ± 48.5

0.24

eGFR (ml/min/1.73 m2)

131.7 ± 41.0

137.0 ± 33.2

0.21

Hypertensive heart disease, n(%)

6 (8.8%)

2 (5.1%)

0.32

Ischemic heart disease, n(%)

31 (44.9%)

13 (33.3%)

0.71

Hypertensive Nephropathy,n(%)

26 (42.6%)

10 (27.8%)

0.31

Peripheral vascular disease, n(%)

11 (16.7%)

2 (5.1%)

0.19

Cerebrovascular disease, n(%)

27 (50.0%)

18 (51.4%)

0.13

Metabolic syndrome, n(%)

6 (8.8%)

2 (5.1%)

1.0

  1. Continuous variables are expressed as the mean ± SD or the medians [interquartile range] unless noted otherwise
  2. Abbreviations: LI Lateralization index, BMI body mass index, CCT captopril challenge test, SIT saline infusion test, ARR ratio of aldosterone/renin, PAC plasma aldosterone concentration, DRC direct renin concentration, ACR urinary albumin/creatinine ratio