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Table 2 Comparison of general material and biochemical indexes of each subgroup

From: Correlational study on the levels of 25-hydroxyvitamin D and non-alcoholic fatty liver disease in type 2 diabetic patients

 

T2DM with NAFLD (n = 231)

Simple T2DM (n = 108)

P value

NFS < 0.676(n = 183)

NFS ≥ 0.676(n = 48)

Sex (male/female)

107/76

27/21

58/50

0.729

Age (years)

54.4 ± 10.9##

67.9 ± 11.2**

63.2 ± 10.8

0.000

Diabetic duration (years)

7.0 (3.0–12.0)##

11.0 (7.0–17.0)**

10.0 (5.0–15.0)

0.000

BMI (kg/m2)

26.60 ± 3.27##

27.93 ± 3.14*

24.69 ± 3.38

0.000

Systolic pressure(mmHg)

132 (122–144)

133 (123–155)

132 (120–152)

0.330

Diastolic pressure(mmHg)

83.2 ± 9.6

81.1 ± 12.0

82.1 ± 10.2

0.374

Waistline(cm)

93 (87–99)##

96 (90–101)

90 (85–95)

0.000

ALT(U/L)

21 (16–32)##

18 (13–30)*

15 (12–22)

0.000

AST(U/L)

18 (15–22)

20 (16–27)*

17 (14–21)

0.006

GGT (U/L)

31.0 (22.0–49.0)##

25.5 (18.0–42.8)

18.5 (13.0–28.0)

0.000

CR (umol/L)

56.0 (47.6–65.1)##

64.2 (53.7–79.9)**

62.8 (49.8–72.3)

0.000

UA (umol/L)

315.5 ± 91.9

356.9 ± 82.7**

304.1 ± 101.6

0.005

CysC (mg/L)

0.88 (0.79–0.98)##

1.09 (0.93–1.37)**

0.97 (0.83–1.17)

0.000

FBG (mmol/L)

8.21 (6.55–11.35)##

7.59 (5.70–9.89)

6.86 (5.59–9.84)

0.003

TG (mmol/L)

1.98 (1.31–2.84)##

1.68 (1.12–2.64)

1.20 (0.89–1.58)

0.000

TC (mmol/L)

4.90 ± 1.12#

4.69 ± 1.02

4.56 ± 1.21

0.037

HDL (mmol/L)

1.01 (0.86–1.17)##

1.05 (0.85–1.30)

1.10 (0.98–1.39)

0.000

LDL (mmol/L)

2.90 ± 0.83

2.81 ± 0.85

2.69 ± 1.04

0.167

HOMA-IR (CP)

3.90 (3.10–5.13)##

3.67 (3.06–4.54)

2.82 (2.45–3.67)

0.000

HBA1C (%)

8.7 (7.2–9.9)

8.2 (6.9–9.5)

7.7 (6.6–9.5)

0.042

25-(OH) D (ng/mL)

14.92 (11.72–18.64)#

13.97 (11.21–15.86)*

16.21 (12.22–22.59)

0.005

  1. The measured data of the normal distribution was represented by mean ± SD. Measurement data for non-normal distributions were expressed as medians (interquartile intervals).*p < 0.05, **p < 0.01, T2DM with NFS ≥ 0.676 vs T2DM with NFS < 0.676; p < 0.05, p < 0.01,T2DM with NFS ≥ 0.676 vs Simple T2DM;#p < 0.05, ##p < 0.01, T2DM with NFS < 0.676 vs Simple T2DM
  2. Note: NAFLD Nonalcoholic fatty liver disease, T2DM Type 2 diabetes mellitus, BMI Body mass index, NFS NAFLD fibrosis score, ALT Alanine aminotransferase, AST Aspartic acid aminotransferase, GGT Glutamyltransferase, CR Creatinine, UA Uric acid, CysC Cystatin c, FBG Fasting blood glucose, TG Triglyceride, TC Total cholesterol, HDL High density lipoprotein, LDL Low density lipoprotein, Homa-IR (CP) Homeostasis model assessment for insulin resistance(C-peptide), HbA1c Glycosylatedhemoglobin, 25-(OH) D 25- hydroxyvitamin D