Characteristic | No of participants | HR (95%CI) | P value | P for interaction |
---|---|---|---|---|
Age (years) | 0.8253 | |||
  < 45 | 10,424 | 1.217 (0.876, 1.691) | 0.2420 |  |
 45–60 | 9796 | 1.093 (0.908, 1.315) | 0.3490 |  |
  ≥ 60 | 8134 | 1.047 (0.907, 1.208) | 0.5317 |  |
Gender | 0.7122 | |||
 Male | 39,072 | 1.068 (0.975, 1.170) | 0.1587 |  |
 Female | 198 | 0.847 (0.341, 2.106) | 0.7213 |  |
BMI (Kg/m2) | 0.2095 | |||
  < 25 | 16,382 | 1.038 (0.840, 1.283) | 0.7305 |  |
  ≥ 25, < 29.9 | 12,466 | 1.027 (0.899, 1.175) | 0.6916 |  |
  ≥ 29.9 | 624 | 0.676 (0.441, 1.035) | 0.0715 |  |
FPG (mmol/L) | 0.3394 | |||
  < 6.1 | 48,902 | 1.162 (1.029, 1.312) | 0.0154 |  |
  ≥ 6.1 | 590 | 1.052 (0.774, 1.430) | 0.7455 |  |
eGFR (ml/min/1.73 m^2) | 0.1310 | |||
  < 90 | 2316 | 0.899 (0.678, 1.193) | 0.4616 |  |
  ≥ 90 | 42,158 | 1.137 (1.026, 1.260) | 0.0143 |  |
BUN (mmol/L) | 0.0675 | |||
  < 7.1 | 10,374 | 0.708 (0.476, 1.052) | 0.0874 |  |
  ≥ 7.1 | 26,662 | 1.053 (0.957, 1.159) | 0.2911 |  |
ALT(U/L) | 0.7811 | |||
  < 40 | 36,772 | 1.102 (0.990, 1.227) | 0.0751 |  |
  ≥ 40 | 2380 | 1.023 (0.743, 1.409) | 0.8886 |  |
AST(U/L) | 0.5111 | |||
  < 40 | 9038 | 1.123 (0.918, 1.373) | 0.2607 |  |
  ≥ 40 | 78 | 1.011 (0.353, 2.901) | 0.9832 |  |
 Not record | 18,880 | 0.935 (0.819, 1.066) | 0.5641 |  |
TC (mmol/L) | 0.5027 | |||
  < 6.22 | 48,008 | 1.092 (0.999, 1.194) | 0.0521 |  |
  ≥ 6.22 | 518 | 0.678 (0.312, 1.473) | 0.3257 |  |
TG (mmol/L) | 0.5843 | |||
  < 2.66 | 35,572 | 1.071 (0.953, 1.203) | 0.2513 |  |
  ≥ 2.66 | 3440 | 0.994 (0.788, 1.255) | 0.9612 |  |
HDL-C (mmol/L) | 0.9791 | |||
  < 1.04 | 588 | 0.984 (0.474, 2.042) | 0.9659 |  |
  ≥ 1.04 | 12,444 | 1.035 (0.883, 1.212) | 0.6713 |  |
 Not recorded | 11,022 | 0.953 (0.774, 1.173) | 0.6496 |  |
LDL-C (mmol/L) | 0.1366 | |||
  < 4.14 | 17,236 | 1.094 (0.961, 1.245) | 0.1758 |  |
  ≥ 4.14 | 54 | 0.000 (0.000, Inf) | 0.9999 |  |
 Not recorded | 10,506 | 1.022 (0.820, 1.274) | 0.8449 |  |
Smoking status | 0.5709 | |||
 Current/Ever smoker | 662 | 1.295 (0.492, 3.412) | 0.6008 |  |
 Never smoker | 1954 | 1.134 (0.650, 1.978) | 0.6581 |  |
 Not recorded | 29,142 | 1.165 (1.055, 1.287) | 0.0026 |  |
Drinking status | 0.6793 | |||
 Current/Ever drinker | 238 | 1.613 (0.446, 5.832) | 0.4656 |  |
 Never drinker | 2944 | 1.043 (0.734, 1.481) | 0.8139 |  |
 Not recorded | 29,142 | 1.165 (1.055, 1.287) | 0.0026 |  |