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Table 4 Predictive ability of the risk score system for CPP in training and validation samples

From: Clinical risk score for central precocious puberty among girls with precocious pubertal development: a cross sectional study

 

Training Sample (n = 314)

Validation Sample (n = 313)

C-index (95%CI)

0.85 (0.81, 0.89)

0.86 (0.82, 0.90)

Calibration

a = −0.02, b = 1.02

a = −0.02, b = 1.06

Cutoff point = 10

 Sensitivity (%, 95CI)

97.8 (95.3, 99.5)

100.0 (−)

 Specificity (%, 95CI)

24.8 (18.2, 32.6)

27.7 (20.2, 34.9)

 Positive likelihood ratio (95%CI)

1.30 (1.20, 1.46)

1.38 (1.25, 1.54)

 Negative likelihood ratio (95%CI)

0.09 (0.02, 0.20)

0.0 (−)

 Positive predictive value (%, 95CI)

61.2 (55.9, 67.0)

62.6 (56.8, 68.6)

 Negative predictive value (%, 95CI)

90.2 (79.2, 97.7)

100.0 (−)

Cutoff point = 20

 Sensitivity (%, 95CI)

39.6 (32.0, 46.2)

34.8 (27.8, 42.1)

 Specificity (%, 95CI)

96.6 (92.9, 99.2)

97.3 (94.2, 100.0)

 Positive likelihood ratio (95%CI)

12.0 (5.49, 48.9)

12.6 (5.44, 48.8)

 Negative likelihood ratio (95%CI)

0.63 (0.55, 0.71)

0.67 (0.59, 0.75)

 Positive predictive value (%, 95CI)

93.3 (86.5, 98.4)

93.9 (86.6, 100.0)

 Negative predictive value (%, 95CI)

56.9 (50.8, 62.9)

55.2 (48.8, 61.4)