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Table 3 Allelic relationship between IL-6 (−174) G/C and IL-10 (−1082) G/A polymorphism and the odds of developing T2DM, North West Ethiopia, 2018 (n = 150)

From: Association of IL-10 (− 1082 A/G) and IL-6 (− 174 G/C) gene polymorphism with type 2 diabetes mellitus in Ethiopia population

Allele

T2DM (N = 75)

N (%)

Controls (N = 75)

N (%)

Fishers exact test

OR (95%CI)

IL-6 (−174)

 G

96 (64)

58 (39)

< 0.001**

2.82 (1.78–4.50)

 C

54 (36)

92 (61)

  

IL-10 (−1082)

 A

36 (23)

60 (40)

0.004**

0.47 (0.29–0.78)

 G

114 (77)

90 (60)

  
  1. T2DM Type 2 Diabetes Mellitus, N Number, CI confidence interval, OR Odd ratio, ** highly significant (P < 0.001)