Table 6 Independent prognostic factors of OS and CSS in postoperative PTL patients via univariate and multivariate Cox regression analysis
(A) Univariate Analysis | (B) Multivariate Analysis | |||||||
|---|---|---|---|---|---|---|---|---|
Overall Survival | Cancer-Specific Survival | Overall Survival | Cancer-Specific Survival | |||||
HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | |
Sex | ||||||||
Male vs. Female | 1.13(0.88–1.44) | 0.338 | 1.05(0.80–1.37) | 0.741 | / | / | / | / |
Age at diagnosis | ||||||||
< 64 vs. > = 64 | 4.91(3.74–6.44) | < 0.001 | 3.89(2.95–5.14) | < 0.001 | 4.71(3.57–6.20) | < 0.001 | 3.83(2.89–5.08) | < 0.001 |
Race | ||||||||
White vs. Black | 1.05(0.50–2.22) | 0.900 | 0.90(0.37–2.18) | 0.811 | / | / | / | / |
White vs. Others | 1.02(0.66–1.59) | 0.924 | 0.81(0.47–1.38) | 0.435 | / | / | / | / |
Marital status | ||||||||
Unmarried vs. Married | 0.49(0.39–0.61) | < 0.001 | 0.66(0.52–0.85) | 0.001 | 0.57(0.46–0.71) | < 0.001 | 0.77(0.60–0.98) | < 0.001 |
Classification | ||||||||
HL vs. Aggressive B cell NHL | 1.91(0.47–7.67) | 0.365 | 1.46(0.36–5.9) | 0.594 | / | / | / | / |
HL vs. Indolent B cell NHL | 1.00(0.25–4.08) | 0.997 | 1.05(0.26–4.35) | 0.951 | / | / | / | / |
HL vs. T cell NHL | 1.25(0.11–13.83) | 0.854 | 0.00(0.00–575.23) | 0.948 | / | / | / | / |
HL vs. NHL-NOS | 2.16(0.50–9.31) | 0.302 | 1.22(0.27–5.59) | 0.794 | / | / | / | / |
HL vs. Others | 1.06(0.19–5.78) | 0.947 | 0.79(0.13–4.73) | 0.796 | / | / | / | / |
Lymphoma Ann Arbor Stage | ||||||||
Stage I vs. Stage II | 1.28(1.00–1.62) | 0.047 | 1.09(0.83–1.42) | 0.532 | 1.38(1.08–1.75) | 0.009 | 1.16(0.88–1.52) | 0.294 |
Stage I vs. Stage III | 0.98(0.50–1.92) | 0.955 | 0.99(0.49–2.01) | 0.971 | 0.68(0.34–1.33) | 0.259 | 0.71(0.35–1.46) | 0.353 |
Stage I vs. Stage IV | 1.84(1.25–2.71) | 0.002 | 1.72(1.13–2.63) | 0.012 | 1.67(1.13–2.47) | 0.009 | 1.57(1.03–2.40) | 0.037 |
Surgery | ||||||||
Lobectomy and/or isthmectomya | Reference | Reference | Reference | Reference | ||||
Removal of less than a lobeb | 1.44(1.06–1.96) | 0.020 | 1.45(1.02–2.04) | 0.037 | 1.59(1.17–2.17) | 0.003 | 1.55(1.10–2.19) | 0.013 |
Removal of more than a lobec | 1.25(0.90–1.74) | 0.193 | 1.22(0.85–1.77) | 0.286 | 1.40(1.00–1.95) | 0.049 | 1.37(0.94–1.98) | 0.099 |
Total thyroidectomy | 0.79(0.59–1.04) | 0.095 | 0.92(0.68–1.25) | 0.602 | 1.00(0.75–1.33) | 1.000 | 1.08(0.79–1.46) | 0.639 |
Others | 0.96(0.45–2.06) | 0.917 | 1.35(0.65–2.77) | 0.422 | 0.90(0.42–1.94) | 0.785 | 1.20(0.58–2.49) | 0.631 |
Chemotherapy | ||||||||
No vs. Performed | 0.90(0.72–1.12) | 0.342 | 0.87(0.68–1.11) | 0.258 | / | / | / | / |
Radiation | ||||||||
No vs. Performed | 0.78(0.63–0.97) | 0.028 | 0.75(0.59–0.95) | 0.019 | 0.77(0.61–0.96) | 0.021 | 0.74(0.58–0.95) | 0.018 |