Table 5 Independent prognostic factors of OS and CSS in post-chemotherapy PTL patients via univariate and multivariate Cox regression analysis
(A) Univariate Analysis | (B) Multivariate Analysis | |||||||
|---|---|---|---|---|---|---|---|---|
Overall Survival | Cancer-Specific Survival | Overall Survival | Cancer-Specific Survival | |||||
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
Sex | ||||||||
Male vs. Female | 1.15(0.92–1.43) | 0.213 | 1.01(0.71–1.43) | 0.969 | / | / | / | / |
Age at diagnosis | ||||||||
< 65 vs. > = 65 | 4.74(3.72–6.03) | < 0.001 | 0.26(0.18–0.39) | < 0.001 | 4.45(3.47–5.69) | < 0.001 | 3.84(2.60–5.69) | < 0.001 |
Race | ||||||||
White vs. Black | 1.13(0.59–2.20) | 0.710 | 1.46(0.54–3.94) | 0.458 | / | / | / | / |
White vs. Others | 1.31(0.91–1.88) | 0.147 | 1.31(0.73–2.38) | 0.365 | / | / | / | / |
Marital status | ||||||||
Unmarried vs. Married | 0.60(0.49–0.73) | < 0.001 | 0.94(0.68–1.31) | 0.720 | 0.74(0.60–0.90) | 0.003 | / | / |
Classification | ||||||||
HL vs. Aggressive B cell NHL | 4.47(1.11–17.94) | 0.035 | 1.53(0.38–6.19) | 0.551 | 2.20(0.54–8.91) | 0.270 | / | / |
HL vs. Indolent B cell NHL | 2.77(0.67–11.41) | 0.158 | 0.55(0.12–2.50) | 0.437 | 1.52(0.37–6.30) | 0.565 | / | / |
HL vs. T cell NHL | 9.54(1.34–67.88) | 0.024 | 3.32(0.30–36.67) | 0.328 | 6.43(0.90–45.87) | 0.063 | / | / |
HL vs. NHL-NOS | 5.16(1.23–21.58) | 0.025 | 1.49(0.33–6.80) | 0.608 | 2.15(0.51–9.08) | 0.298 | / | / |
HL vs. Others | 5.49(1.22–24.77) | 0.027 | 1.78(0.33–9.74) | 0.504 | 2.81(0.62–12.78) | 0.183 | / | / |
Lymphoma Ann Arbor Stage | ||||||||
Stage I vs. Stage II | 0.96(0.76–1.20) | 0.730 | 1.39(0.96–2.01) | 0.078 | 1.07(0.86–1.34) | 0.527 | 1.48(1.02–2.13) | 0.038 |
Stage I vs. Stage III | 0.98(0.59–1.63) | 0.936 | 1.41(0.64–3.10) | 0.394 | 0.92(0.55–1.53) | 0.736 | 1.21(0.55–2.68) | 0.636 |
Stage I vs. Stage IV | 1.58(1.16–2.15) | 0.003 | 2.20(1.35–3.59) | 0.002 | 1.19(0.87–1.62) | 0.279 | 1.69(1.03–2.77) | 0.039 |
Surgery | ||||||||
No vs. Performed | 0.70(0.58–0.86) | < 0.001 | 0.75(0.54–1.04) | 0.085 | 0.82(0.67–1.00) | 0.050 | / | / |
Radiation | ||||||||
No vs. Performed | 0.66(0.55–0.81) | < 0.001 | 0.56(0.40–0.79) | 0.001 | 0.64(0.53–0.79) | < 0.001 | 0.56(0.40–0.79) | 0.001 |