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Table 4 Multivariable ordinal logistic regression to investigate the association between RVE1 and TPOAb

From: Serum resolvin E1 levels and its relationship with thyroid autoimmunity in Hashimoto’s thyroiditis: a preliminary study

Interquartile range of

TPOAb

Q1 (< 13.6 U/mL)

(n = 14)

Q2 (13.6–106 U/mL)

(n = 14)

Q3 (106–431 U/mL)

(n = 15)

Q4 (> 431 U/mL)

(n = 14)

 

b RVE1 Levels

26.16 (19.53–38.64)

31.39 (23.79–62.31)

28.51 (17.03–40.38)

19.21 (15.11–26.01) *

a P for trend = 0.036

Multivariable ordinal logistic regression

 

β (95 % CI)

OR (95 % CI)

P value

Model 1

-0.024 (-0.045, -0.003)

0.9762 (0.9559, 0.9970)

0.028

Model 2

-0.023 (-0.044, -0.002)

0.9772 (0.9569, 0.9980)

0.011

Model 3

-0.014 (-0.038, 0.010)

0.9860 (0.9627, 1.010)

0.244

  1. According to the interquartile range, TPOAb was divided into four groups: Q1: the first TPOAb quartile group (TgAb < 13.6 U/mL), Q2: the second TPOAb quartile group (13.6–10.6 U/mL), Q3: the third TPOAb quartile group (10.6–431 U/mL), Q4: the fourth TPOAb quartile group (> 431 U/mL)
  2. aThe Jonckheere-Terpstra test was used to evaluate trends in RVE1 levels when TPOAb levels increased
  3. b Results are expressed as medians (interquartile ranges). The Kruskal-Wallis test was used to detect differences in RVE1 levels among the four groups, and Bonferroni‐adjusted P values were used, *p = 0.019 vs. Q2 group
  4. Multivariable ordinal logistic regression models were used to evaluate relationships between RVE1 and increasing TPOAb levels. Model 1 was not adjusted for other variables; Model 2 was adjusted for age and sex; Model 3 was adjusted for age, sex, TT3, TT4, TSH, FT3, FT4 and TPOAB. RVE1, resolvin E1; OR, odds ratio; 95 % CI, 95 % confidence interval
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BMC Endocrine Disorders

ISSN: 1472-6823

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