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Table 3 Multivariable ordinal logistic regression to investigate the association between RVE1 and TgAb

From: Serum resolvin E1 levels and its relationship with thyroid autoimmunity in Hashimoto’s thyroiditis: a preliminary study

Interquartile range of TgAb Q1 (< 12.9 U/mL)
(n = 14)
Q2 (12.9–79.1 U/mL)
(n = 14)
Q3 (79.1–361 U/mL)
(n = 15)
Q4 (> 361 U/mL)
(n = 14)
 
b RVE1 Levels 37.70 (24.66–99.16) 26.46 (18.91–34.87) 28.51 (19.53–37.61) 19.21 (13.81–27.34) * a P for trend = 0.001
Multivariable ordinal logistic regression
  β (95 % CI) OR (95 % CI) P value
Model 1 -0.057 (-0.093, -0.022) 0.9446 (0.9111, 0.9782) 0.002
Model 2 -0.054 (-0.087, -0.021) 0.9475 (0.9166, 0.9792) 0.001
Model 3 -0.064 (-0.109, -0.019) 0.9380 (0.8967, 0.9811) 0.005
  1. According to the interquartile range, TgAb was divided into four groups: Q1: the first TgAb quartile group (TgAb < 12.9 U/mL), Q2: the second TgAb quartile group (12.9–79.1 U/mL), Q3: the third TgAb quartile group (79.1–361 U/mL), Q4: the fourth TgAb quartile group (> 361 U/mL)
  2. aThe Jonckheere-Terpstra test was used to evaluate trends of RVE1 levels when the TgAb level increased
  3. b Results are expressed as medians (interquartile ranges). The Kruskal-Wallis test was used to detect differences in RVE1 levels among the four groups, and Bonferroni‐adjusted P values were used, *P = 0.005 vs. Q1 group
  4. Multivariable ordinal logistic regression models were used to evaluate relationships between RVE1 and increasing TgAb levels. Model 1 was not adjusted for other variables; Model 2 was adjusted for age and sex; Model 3 was adjusted for age, sex, TT3, TT4, TSH, FT3, FT4 and TPOAB. RVE1, resolvin E1; OR, odds ratio; 95 % CI, 95 % confidence interval