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Table 2 Baseline characters of the patients in the included studies

From: Lithium carbonate as add-on therapy to radioiodine in the treatment on hyperthyroidism: a systematic review and meta-analysis

Study ID

Study groups

Age (years)

Mean (SD)

Gender (males)

Number, percentage

The onset of hyperthyroidism (years)

Mean (SD)

Mean thyroid volume (ml)

Mean (SD)

Mean serum TSH (mIU/l)

Mean (SD)

Randomized controlled trials

Thamcharoenvipas et al 2019

Intervention 1

30 (7.4)

3, 15%

21.3 (32.6)

82.6 (30.4)

.005 (.006)

Intervention 2

34.3 (13)

1, 5%

30.3 (39.3)

87.1 (21.0)

.011 (.02)

control

31.8 (12.2)

8, 40%

15.2 (19.6)

98.9 (36.0)

.003 (.004)

Hammond et al. 2016

intervention

43.7 (13.2)

9, 10%

NA

NA

.05

control

48.4 (12.0)

11, 14.7%

NA

NA

.04

Lingudu et al. 2014

intervention

35.9 (7.5)

2, 10%

19.7 (21)

26.7 (15.8)

NA

control

37.3 (12.7)

9, 45%

15.5 (10.8)

28.2 (12.4)

NA

Bal et al. 2002

intervention

41.8 (12.2)

61, 37.2%

6.1 (47.9)

48 (29.0)

NA

control

41.8 (11.5)

54, 35.5%

45.4 (41.6)

45 (24.0)

NA

Bogazzi et al. 2002

Intervention 1

48.0 (9.0)

2, 16.7%

37.3 (2.4)

19 (10)

1.3 (1.3)

Intervention 2

51.0 (9.0)

3, 25%

5.7 (2.0)

21 (11.0)

1.4 (1.7)

control

52.0 (13.0)

4, 33.4%

5.3 (1.8)

24 (13.0)

2.3 (1.8)

Bogazzi et al. 1999

Intervention

45 (12.8)

10, 18.5%

6.1 (2.3)

38 (22.0)

.6 (1.0)

Control

51 (15.8)

9, 16.7%

5.7 (2.3)

35 (21.0)

.4 (.9)

Non-randomized controlled trials

Sekulić et al 2017

Intervention

53.9 (8.8)

5, 16.7%

84.2 (68.0)

NA

.9 (.6)

Control

51.3 (9.2)

6, 20%

72.6 (52.6)

NA

.9 (.88)

Oszukowska et al 2010

Intervention

52.1 (13.1)

29 (14.5%)

NA

NA

NA

Control

NA

NA

NA

TURNER et al 1976

Intervention

44 (10.3)

5, 31.3%

NA

NA

NA

Control

43 (7.8)

2, 12.5%

NA

NA

NA

  1. Data is expressed as mean and standard deviation (SD) or frequency and percentage. NA: not availabe