Table 1 Demographic Data and Clinical Features of the Groups
Characteristics | PCOS (n = 46) | PCOS + HT (n = 46) | P value | |
|---|---|---|---|---|
Age, mean ± SD, years | 26.4 ± 3.8 | 27.7 ± 3.2 | 0.072 | |
Body mass index, mean ± SD, kg/m2 | 26.8 ± 5.4 | 27.1 ± 4.7 | 0.773 | |
Waist/hip ratio, mean ± SD | 0.75 ± 0.06 | 0.76 ± 0.07 | 0.737 | |
Cigarette, n(%) | ||||
No | 22 (47.8) | 25 (54.3) | 0.532 | |
Yes | 24 (52.2) | 21 (45.7) | ||
Chronic disease, n(%) | ||||
No | 39 (84.8) | 29 (63) | 0.060 | |
Asthma | 5 (10.9) | 7 (15.2) | ||
Diabetes type 2 | 0 | 2 (4.3) | ||
Other | 2 (4.3) | 8 (17.4) | ||
Chronic Medication Use, n(%) | ||||
No | 38 (82.6) | 29 (63) | 0.035 | |
Yes | 8 (17.4) | 17 (37) | ||
Menarche Age, mean ± SD, years | 13 ± 1.1 | 13.2 ± 1.2 | 0.52 | |
Menstrual Pattern, n(%) | ||||
Regular | 7 (15.3) | 12 (26.1) | 0.260 | |
Oligo/ amenorrhea | 37 (80.4) | 33 (71.7) | ||
Polymenorrhea | 2 (4.3) | 1 (2.2) | ||
Acne, n(%) | ||||
No | 23 (50) | 26 (56.5) | 0.457 | |
Yes | 23 (50) | 19 (41.3) | ||
Hirsutism Score (mean ± SD) | 8.2 ± 4.8 | 8.5 ± 4.3 | 0.787 | |
Fertility n(%) | ||||
Fertile | 20 (43.5) | 8 (17.4) | 0.007 | |
Pr. infertile | 15 (32.6) | 29 (63) | ||
Sec. infertile | 11 (23.9) | 9 (19.6) | ||
İnfertility period, year±SD | 2.2 ± 1.5 | 2.5 ± 2.7 | 0.477 | |
Gravida | 1 (0–4) | 0 (0–3) | < 0.001 | |
Parity | 1 (0–3) | 0 (0–3) | < 0.001 | |
Abortion | 0 (0–2) | 0 (0–1) | 0.14 | |
Family history of autoimmune thyroiditis, n(%) | ||||
No | 35 (76.1) | 20 (43.5) | 0.001 | |
Yes | 11 (23.9) | 26 (56.5) | ||
Family history of autoimmune disease, n(%) | ||||
No | 26 (56.5) | 21 (45.7) | 0.297 | |
Yes | 20 (43.5) | 25 (54.3) | ||
HT period, year, median (min-max) mean ± SD | 0 | 1.5 (0–10) | 2.6 ± 2.9 | |
Thyroid Hormone Replacement (THR), n(%) | ||||
No | 46 (100) | 20 (43.5) | < 0.001 | |
Yes | 0 | 26 (56.5) | ||
THR time, year | 0 | 1 (0–16) | 2.1 ± 3.2 | |