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Table 1 Baseline clinical, biological, and medication characteristics

From: The impact of subclinical hypothyroidism on long-term outcomes in older patients undergoing percutaneous coronary intervention

 

SCH

(n = 320)

ET

(n = 2848)

P Value

Clinical characteristics

 Age, years

70.4 ± 4.0

70.9 ± 4.2

0.038

 Female, n (%)

186 (58.1)

1152 (40.4)

0.000

 BMI, kg/m2,

26.4 ± 3.2

25.5 ± 3.0

0.000

 Hypertension, n (%)

248 (77.5)

2128 (74.7)

0.276

 Diabetes mellitus, n (%)

100 (31.3)

932 (32.7)

0.594

 Hyperlipidemia, n (%)

174 (54.4)

1306 (45.9)

0.004

 Current smoking, n (%)

58 (18.1)

572 (20.1)

0.405

 Family history of CAD, n (%)

16 (5.0)

174 (6.1)

0.428

 History of MI, n (%)

28 (8.8)

352 (12.4)

0.060

 History of PCI, n (%)

44 (13.8)

496 (17.4)

0.098

 History of CABG, n (%)

4 (1.3)

74 (2.6)

0.140

 History of Stroke, n (%)

36 (11.3)

358 (12.6)

0.497

 History of HF, n (%)

26 (8.1)

177 (6.2)

0.186

 History of RF, n (%)

12 (3.8)

136 (4.8)

0.410

 SAP, n (%)

40 (12.5)

414 (14.5)

0.324

 UAP, n (%)

216 (67.5)

1928 (67.7)

0.943

 AMI, n (%)

64 (20.0)

506 (17.8)

0.324

 LVEF, (%)

63.6 ± 7.8

63.0 ± 9.1

0.265

Laboratory characteristics

 TSH

7.19 (6.20–8.28)

1.64 (1.10–2.46)

0.000

 FT3

4.80 (4.20–5.40)

4.90 (4.30–5.40)

0.301

 FT4

11.00 (9.33–12.80)

11.00 (9.40–12.70)

0.879

 Hemoglobin, g/dl

129 (123, 142)

137 (127, 147)

0.000

 Fasting glucose, mmol/L

5.57 (5.03, 6.49)

5.62 (5.09, 6.51)

0.478

 Creatinine, μmol/L

74.5 (62.0, 89.0)

76.0 (65.0, 89.0)

0.206

 TC, mmol/L

4.50 (4.04, 5.15)

4.30 (3.64, 5.01)

0.000

 TG, mmol/L

1.50 (1.56, 1.97)

1.39 (1.03, 1.88)

0.002

 LDL-C, mmol/L

2.61 (2.25, 3.11)

2.58 (2.01, 3.11)

0.018

 HDL-C, mmol/L

1.14 (1.01, 1.34)

1.09 (0.94, 1.26)

0.000

 HsCRP, mg/L

2.00 (0.71, 4.83)

1.75 (0.69, 4.60)

0.221

Medications at discharge

 Aspirin, n (%)

318 (99.4)

2842 (99.8)

0.416

 Clopidogrel, n (%)

318 (99.4)

2843 (99.8)

0.319

 ß-Blocker, n (%)

256 (80.0)

2200 (77.2)

0.263

 ACEI/ARB, n (%)

174 (54.4)

1562 (54.8)

0.873

 Calcium channel antagonist, n (%)

102 (31.9)

796 (27.9)

0.140

 Nitrates, n (%)

198 (61.9)

1866 (65.5)

0.195

 Statins, n (%)

308 (96.3)

2732 (95.9)

0.781

  1. Data are expressed as mean ± SD, medians with inter quartile ranges or percentage. BMI body mass index, CAD coronary artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, HF hear failure, RF renal failure, SAP stable angina pectoris, UAP unstable angina pectoris, AMI acute myocardial infarction, LVEF left ventricle ejection fraction, TC total cholesterol, TG triglyceride, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, HsCRP high-sensitivity C-reactive protein, ACE-I angiotensin II coenzyme inhibitor, ARB angiotensin II receptor blocker