From: Thyroid function and non-alcoholic fatty liver disease in hyperthyroidism patients
FT3 | T1(≦12.70 pmol/L) | T2(12.71 ~ 25.80 pmol/L) | T3(>25.80 pmol/L) | P for trend |
---|---|---|---|---|
Age (years) | 49.9 ± 11.9 | 46.1 ± 13.8 | 40.1 ± 10.8※☆ | 0.002 |
Gender(M/F) | 14/25 | 11/28 | 9/30 | 0.455 |
FT4(pmol/L) | 25.28 ± 10.26 | 48.41 ± 14.11※ | 88.78 ± 17.28※☆ | < 0.001 |
TSH (uIU/ml) | 0.01 (0.005,1.470) | 0.005 (0.005, 0.010)※ | 0.005 (0.005, 0.010)※ | < 0.001 |
BMI (kg/m2) | 23.41 ± 3.30 | 23.40 ± 3.41 | 20.85 ± 2.82※☆ | < 0.001 |
Waist circumference (cm) | 83.17 ± 8.82 | 81.43 ± 10.19 | 77.79 ± 8.95※ | 0.113 |
SBP (mmHg) | 121.46 ± 13.26 | 124.72 ± 10.94 | 121.38 ± 16.68 | 0.480 |
DBP (mmHg) | 74.92 ± 9.10 | 75.79 ± 8.54 | 72.26 ± 10.21 | 0.221 |
FBG (mmol/L) | 5.01 ± 1.30 | 5.01 ± 0.79 | 5.25 ± 1.09 | 0.541 |
f-INS (mU/L) | 8.30 (5.50, 9.70) | 7.90 (5.80, 11.1) | 9.20 (7.00, 11.00) | 0.367 |
TG (mmol/L) | 1.03 ± 0.48 | 1.14 ± 0.58 | 0.79 ± 0.28※☆ | 0.006 |
TC (mmol/L) | 3.91 ± 0.85 | 3.47 ± 0.77※ | 2.94 ± 0.43※☆ | < 0.001 |
LDL (mmol/L) | 2.23 ± 0.63 | 1.76 ± 0.62※ | 1.36 ± 0.38※☆ | < 0.001 |
IL6(pg/ml) | 2.20 (2.00,3.00) | 2.10 (2.00,2.58) | 2.60 (2.10,3.38) | 0.352 |
HCRP (mg/L) | 0.80 (0.40,1.98) | 0.70 (0.30,2.20) | 1.00 (0.45,2.15) | 0.389 |
UA (umol/L) | 295.90 ± 77.90 | 282.28 ± 56.85 | 300.68 ± 72.63 | 0.486 |
ALT(U/L) | 24.92 ± 19.76 | 36.79 ± 26.95※ | 48.69 ± 43.93※ | 0.006 |
AST(U/L) | 21.46 ± 10.29 | 26.36 ± 13.41 | 33.62 ± 21.91※ | 0.004 |
Liver fat content(%) | 6.75 ± 3.45 | 6.14 ± 4.34 | 4.01 ± 2.43※☆ | 0.002 |
With NAFLD/without NAFLD | 10/29 | 3/36 | 1/38※ | 0.004 |
HOMA-IR | 1.70 (1.11, 2.64) | 1.76 (1.19, 2.55) | 2.04 (1.63, 2.54) | 0.289 |