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Table 1 RAGR, NF-κB, MMP9, MMP1 and CD68 protein expression levels in myocardial

From: Role of Artesunate on cardiovascular complications in rats with type 1 diabetes mellitus

Group

Mean optical density (MOD)

RAGE

NF-κB

MMP9

MMP1

CD68

Healthy

1.972 ± 0.181

1.778 ± 0.793

2.019 ± 0.548

3.233 ± 0.290

1.058 ± 0.192

DM

6.119 ± 0.984**

6.219 ± 1.517**

8.029 ± 1.563**

6.875 ± 0.259**

6.425 ± 1.179**

DM + ART(50 mg/kg)

3.189 ± 1.451*##

1.796 ± 0.820##

2.062 ± 0.401##

3.330 ± 0.494##

2.203 ± 1.602##

DM + ART(100 mg/kg)

2.435 ± 0.489##

2.809 ± 1.092##

7.787 ± 0.713**

5.002 ± 0.702*#

7.929 ± 0.827**

DM + INS

3.165 ± 0.636*##

6.673 ± 2.364**

4.900 ± 1.164**##

4.095 ± 1.682##

4.056 ± 1.613*#

  1. Results are presented as the mean ± SD. Values of *P < 0.05, **P < 0.01 vs Healthy group. #P < 0.05, ##P < 0.01 vs DM group indicate a significant difference between each groups