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Table 1 Summary of demographics and post-operative outcomes

From: Outcomes of endoscopic transsphenoidal surgery for Cushing's disease

Number of patients undergoing ETSS 39
Number of ETSS procedures 43
Age 37 (8–75)
Female 30 (77%)
Tumour visible on pre-op MRI
Microadenoma
Macroadenoma
22 (56%)
18
4
Pre-operative IPSS 33 (85%)
Postoperative remission, initial ETSS
Standard criteriaa 34 (87%)
Strict criteriab 22 (58%)
Postoperative remission, including 3 patients with early repeat ETSS
Standard criteriaa 36 (92%)
Strict criteriab 23 (61%)
Postoperative hypopituitarism
Transient diabetes insipidus 13 (33%)
Permanent diabetes insipidus 9 (23%)
TSH deficiency 5 (13%)
Gonadotrophin deficiency 4 (10%)
Recurrence 1
  1. Data expressed as median (range) and number (percentage).
  2. a 0800 h serum cortisol < 138 nmol/l within seven days of operation and improvement in clinical features of hypercortisolism
  3. b Day 3 0800 h serum cortisol concentration < 50 nmol/L. Day 3 cortisol was not measured in one patient due to intercurrent illness requiring treatment with intravenous glucocorticoids