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Table 1 Descriptive parameters of the total study population

From: Predictors of dopamine agonist resistance in prolactinoma patients

  

Study population

Responsive group

Resistant group

Demographic factors

Patients

69

58

11

Women

52

46

6

Men

17

12

5

Endocrinological factors

Baseline PRL

[median (interquartile range)]

116.98 μg/l (294,46)

105.66 μg/l (284,17)

259.77 μg/l (842,24)

PRL after 3 months: Reduction

[mean (standard deviation)]

83.3% (20.56)

85.9% [11, 15]

67.5% (31,75)

PRL after 3 months: Normalization

62.0%

70.5%

0.0%

PRL after 4 months: Reduction

[mean (standard deviation)]

82.7% (22,85)

87.4% (18,95)

63.8% (30,32)

PRL after 4 months: Normalization

79.0%

87.5%

0.0%

MRI factors

Tumour volume

[median (interquartile range)]

0.18 cm3 (1,32)

0.13 cm3 (0,88)

3.34 cm3 [5, 7]

Microadenoma

54.4%

59.6%

27.3%

Macroadenoma

45.6%

40.4%

72.7%

Contrast capitation

[mean (standard deviation)]

1.93 (0,81)

1.88 (0,70)

2.40 (1,43)

Presence of cystic/hemorraghic/necrotic component

26.7%

20.7%

71.4%

  1. PRL: Prolactin; Contrast capitation: the ratio of the density factor on T1 after contrast to the value on T1 without contrast