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Table 1 Descriptive parameters of the total study population

From: Predictors of dopamine agonist resistance in prolactinoma patients

  Study populationResponsive groupResistant group
Demographic factorsPatients695811
Women52466
Men17125
Endocrinological factorsBaseline PRL
[median (interquartile range)]
116.98 μg/l (294,46)105.66 μg/l (284,17)259.77 μg/l (842,24)
PRL after 3 months: Reduction
[mean (standard deviation)]
83.3% (20.56)85.9% [11, 15]67.5% (31,75)
PRL after 3 months: Normalization62.0%70.5%0.0%
PRL after 4 months: Reduction
[mean (standard deviation)]
82.7% (22,85)87.4% (18,95)63.8% (30,32)
PRL after 4 months: Normalization79.0%87.5%0.0%
MRI factorsTumour volume
[median (interquartile range)]
0.18 cm3 (1,32)0.13 cm3 (0,88)3.34 cm3 [5, 7]
Microadenoma54.4%59.6%27.3%
Macroadenoma45.6%40.4%72.7%
Contrast capitation
[mean (standard deviation)]
1.93 (0,81)1.88 (0,70)2.40 (1,43)
Presence of cystic/hemorraghic/necrotic component26.7%20.7%71.4%
  1. PRL: Prolactin; Contrast capitation: the ratio of the density factor on T1 after contrast to the value on T1 without contrast