Table 1 Main clinical features and circulating Fetuin-A levels in PCOS and healthy women
Characteristics | Controls (n = 85) | PCOS (n = 122) | p-value |
|---|---|---|---|
Age (yr) | 26.0 ± 3.4 | 25. 3 ± 3.4 | 0.114 |
BMI (kg/m2) | 21.6 ± 2.9 | 24.4 ± 4.4 | < 0.001 |
WHR | 0.81 ± 0.08 | 0.88 ± 0.10 | < 0.001 |
SBP (mmHg) | 113 ± 8 | 128 ± 8 | < 0.001 |
DBP (mmHg) | 75 ± 7 | 77 ± 7 | 0.045 |
TG (mmol/L) | 0.92 (066–1.34) | 1.37(1.01–2.48) | < 0.001 |
TC (mmol/L) | 3.94 ± 0.76 | 4.64 ± 0.93 | < 0.001 |
HDL-C (mmol/L) | 1.23 ± 0.27 | 1.18 ± 0.33 | 0.278 |
LDL-C (mmol/L) | 2.18 ± 0.58 | 2.89 ± 0.58 | < 0.001 |
FBG (mmol/L) | 4.77 ± 0.46 | 5.06 ± 0.91 | < 0.01 |
FIns (mU/L) | 7.40 (5.55–9.17) | 18.00 (9.30–27.08) | < 0.001 |
HOMA-IR | 15.0 (1.15–2.04) | 3.85 (1.97–5.83) | < 0.001 |
FSH (IU/L) | 5.92 ± 2.00 | 5.78 ± 1.36 | 0.574 |
LH (IU/L) | 6.07 ± 5.14 | 8.39 ± 4.94 | < 0.001 |
T (nmol/L) | 1.01 ± 0.68 | 1.44 ± 0.65 | < 0.001 |
DHEA-S (μmol/L) | 4.50 ± 1.86 | 6.58 ± 2.93 | < 0.001 |
Fetuin-A (μg/L) | 313.8 ± 60.5 | 437.9 ± 119.3 | < 0.001 |